منهاجال محمد جاويد عبد المنان عارفين

أعضاء هيئة التدريس

منهاج ال عارفين محمد جاويد

أستاذ مشارك

كلية الصيدلة،

قسم دكتور صيدلي

البيانات الشخصية

المؤهلات العلمية

B. Sc. Chemistry and Botany
B. Pharm.
M. S. (Pharm.) Medicinal Chemistry
Ph. D. Medicinal Chemistry

الاهتمامات البحثية

Selective Human TopoIIα topoisomerase inhibitors
Identification of new Carbocyclic, N-heterocyclic carbenes and r-N-heterocyclic carbenes

الأبحاث المنشورة

Design, classification, and adverse effects of NSAIDs: A review on recent advancements (2024-01-01)
Design, synthesis and biological evaluation of 5-benzylidene-2-iminothiazolidin-4-ones as selective GSK-3β inhibitors (2016-01-01)
Molecular dynamics simulation studies of GSK-3β ATP competitive inhibitors: understanding the factors contributing to selectivity (2015-01-01)
Dihydropyridines as potential α-amylase and α-glucosidase inhibitors: synthesis, in vitro and in silico studies (2020-01-01)
Design of glycogen synthase kinase-3 inhibitors: an overview on recent advancements (2013-01-01)
Design, Synthesis, and Structural Analysis of Divalent NI Compounds and Identification of a New Electron‐Donating Ligand (2016-01-01)
Mechanism of the Paal–Knorr reaction: the importance of water mediated hemialcohol pathway (2015-01-01)
Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme (2014-01-01)
Can Remote N‐Heterocyclic Carbenes Coordinate with Main Group Elements? Synthesis, Structure, and Quantum Chemical Analysis of N+‐Centered Complexes (2018-01-01)
Design, synthesis and biological evaluation of 4-aminoquinoline-guanylthiourea derivatives as antimalarial agents (2019-01-01)
Importance of cytochromes in cyclization reactions: quantum chemical study on a model reaction of proguanil to cycloguanil (2014-01-01)
A metal and base-free chemoselective primary amination of boronic acids using cyanamidyl/arylcyanamidyl radical as aminating species: synthesis and mechanistic studies by … (2016-01-01)
Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies (2017-01-01)
Sukkari dates seed improves type-2 diabetes mellitus-induced memory impairment by reducing blood glucose levels and enhancing brain cholinergic transmission: In vivo and … (2022-01-01)
Neuroprotective effect of methanolic Ajwa seed extract on lipopolysaccharide-induced memory dysfunction and neuroinflammation: In vivo, molecular docking and dynamics studies (2023-01-01)
Carbene →N+ Coordination Bonds in Drugs: A Quantum Chemical Study (2016-01-01)
Piracetam as a therapeutic agent for doxorubicin-induced cognitive deficits by enhancing cholinergic functions and reducing neuronal inflammation, apoptosis, and oxidative … (2022-01-01)
Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular … (2022-01-01)
Phytochemical profiling, molecular docking, and in vitro anti-hepatocellular carcinoid bioactivity of Suaeda vermiculata extracts (2022-01-01)
Aqueous Ajwa dates seeds extract improves memory impairment in type-2 diabetes mellitus rats by reducing blood glucose levels and enhancing brain cholinergic transmission (2022-01-01)
Divalent NI Compounds: Identifying new Carbocyclic Carbenes to Design Nitreones using Quantum Chemical Methods (2020-01-01)
Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial Functions in Mice (2021-01-01)
In vivo and computational studies on sitagliptin’s neuroprotective role in type 2 diabetes mellitus: Implications for Alzheimer’s disease (2024-01-01)
Electronic and ligating properties of carbocyclic carbenes: A theoretical investigation (2019-01-01)
Betahistine’s neuroprotective actions against lipopolysaccharide-induced neurotoxicity: Insights from experimental and computational studies (2024-01-01)
Ciproxifan attenuates the memory impairment induced by lipopolysaccharide through modulation of cholinergic transmission in the mouse brain. (2022-01-01)
Assessing the influence of intermittent alcohol access on acrylamide-induced neuronal toxicity in an experimental rat model (2024-01-01)
Montelukast's potential as a neuroprotective agent against acrylamide induced neurotoxicity: In vivo and computational modelling (2025-01-01)
Multipotent effect of clozapine on lipopolysaccharide-induced acetylcholinesterase, cyclooxygenase-2, 5-lipoxygenase, and caspase-3: In vivo and molecular modeling studies (2025-01-01)
Sertraline as a Multi-Target Modulator of AChE, COX-2, BACE-1, and GSK-3β: Computational and In Vivo Studies (2024-01-01)
Acrylamide exposure exacerbates type 2 diabetes-induced neurotoxicity: an integrated neurobehavioral and molecular investigation (2026-01-01)
Screening of Polyphenolic compounds to identify dual inhibitors against Glycogen Synthase 3β and Acetylcholinesterase for the treatment of Alzheimer's Diseases (2024-01-01)
Multi targeted ligands for potential inhibition of dipeptidyl peptidase 4, acetylcholinesterase and cyclooxygenase 2 (2024-01-01)
Aqueous Extract from Sukkari Date Seeds Attenuates Neuroinflammation Induced by Type-2 Diabetic in Rats (2022-01-01)
Neuroprotective Effect of Aqueous Extract of Ajwa Seeds via Anti-Inflammatory Pathways in Type-2 Diabetic-Induced Rats (2022-01-01)
Modular Approach to In Silico Antiviral Multitargets Inhibitor: Molecular Dockings, Dynamics, Principal Component Analysis, Clustering, and Energy Landscape (2026-01-01)
Levetiracetam mitigates doxorubicin-induced Oxidative stress associated with Cognitive impairments and Neurodegeneration in experimental rats: In vivo and Molecular Modelling … (2024-01-01)
NEUROPROTECTIVE EFFECTS OF HISTAMINE H3 RECEPTOR LIGANDS CIPROXIFAN AND CLOBENPROPIT THROUGH ANTIAPOPTOTIC AND ANTIOXIDANT MECHANISMS: EVIDENCE FROM IN VIVO AND COMPUTATIONAL … (2026-01-01)
Aryloxyethylamines Chalcones as Potential β3 AR Binders: Synthesis, In Vivo Antidiabetic and Molecular Modeling Studies (2026-01-01)
Neuroprotective Effect of Clobenpropit in Lipopolysaccharides- induced Mice via Enhancing Cholinergic Transmission (2022-01-01)
Ciproxifan Attenuates Lipopolysaccharide-Induced Neuroinflammation and Mitochondrial Dysfunctions in Mouse Brain (2022-01-01)
Recent Advances in the Synthesis of Peptides and Proteins (2017-01-01)
NBO 2015–1517 references Compiled by Ariel Andrea on 1/07/2016 (2015-01-01)
Design and Synthesis of Substrate Competitive Inhibitors: Towards Selective GSK-3β Inhibition (2026-01-01)
Rational Design of 2-Imino-5-(2-oxo-2-phenylethyl) thiazolidin-4-one derivatives as Substrate Competitive Inhibitors of GSK-3 (2026-01-01)
Assessing the Influence of Intermittent Alcohol Access on Acrylamide-Induced Neuronal Toxicity in an Experimental Rat Model (2024-06-01)
Sukkari dates seed improves type-2 diabetes mellitus-induced memory impairment by reducing blood glucose levels and enhancing brain cholinergic transmission: In vivo and molecular modeling studies (2022-06-30)
Neuroprotective Effect of Clobenpropit in Lipopolysaccharides-induced Mice via Enhancing Cholinergic Transmission (2022-01-01)
Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial Functions in Mice (2021-12-01)
Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats (2022-12-01)
Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular Docking Study (2022-11-01)
Ciproxifan Attenuates Lipopolysaccharide-Induced Neuroinflammation and Mitochondrial Dysfunctions in Mouse Brain (2022-01-01)
Aqueous Ajwa dates seeds extract improves memory impairment in type-2 diabetes mellitus rats by reducing blood glucose levels and enhancing brain cholinergic transmission (2022-03-21)
Neuroprotective Effect of Aqueous Extract of Ajwa Seeds via Anti-Inflammatory Pathways in Type-2 Diabetic-Induced Rats (2022-01-01)
Aqueous Extract from Sukkari Date Seeds Attenuates Neuroinflammation Induced by Type-2 Diabetic in Rats (2022-01-01)
Montelukast's potential as a neuroprotective agent against acrylamide induced neurotoxicity: In vivo and computational modelling (2025-04-16)
Multipotent Effect of Clozapine on Lipopolysaccharide-Induced Acetylcholinesterase, Cyclooxygenase-2,5-Lipoxygenase, and Caspase-3: In Vivo and Molecular Modeling Studies (2025-01-01)
In Vivo and Computational Studies on Sitagliptin's Neuroprotective Role in Type 2 Diabetes Mellitus: Implications for Alzheimer's Disease (2024-12-01)
Sertraline as a Multi-Target Modulator of AChE, COX-2, BACE-1, and GSK-3β: Computational and In Vivo Studies (2024-11-01)
Betahistine's Neuroprotective Actions against Lipopolysaccharide-Induced Neurotoxicity: Insights from Experimental and Computational Studies (2024-09-01)
Neuroprotective Effect of Methanolic Ajwa Seed Extract on Lipopolysaccharide-Induced Memory Dysfunction and Neuroinflammation: In Vivo, Molecular Docking and Dynamics Studies (2023-02-01)
Modular Approach to In Silico Antiviral Multitargets Inhibitor: Molecular Dockings, Dynamics, Principal Component Analysis, Clustering, and Energy Landscape (2026-02-23)
Design, classification, and adverse effects of NSAIDs: A review on recent advancements (2024-08-31)
Phytochemical profiling, molecular docking, and in vitro anti-hepatocellular carcinoid bioactivity of Suaeda vermiculata extracts (2022-05-19)
Aryloxyethylamines Chalcones as Potential β3 AR Binders: Synthesis, In Vivo Antidiabetic and Molecular Modeling Studies (2026-01-31)
DivalentNICompounds: Identifying new Carbocyclic Carbenes to Design Nitreones using Quantum Chemical Methods (2020-09-10)
Dihydropyridines as potential α-amylase and α-glucosidase inhibitors: Synthesis, in vitro and in silico studies (2020-03-01)
Design, synthesis and biological evaluation of 4-aminoquinoline-guanylthiourea derivatives as antimalarial agents (2019-10-01)
Electronic and ligating properties of carbocyclic carbenes: A theoretical investigation (2019-02-15)
Can Remote N-Heterocyclic Carbenes Coordinate with Main Group Elements? Synthesis, Structure, and Quantum Chemical Analysis of N+-Centered Complexes (2018-04-25)
Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies (2017-07-28)
Carbene →N+ Coordination Bonds in Drugs: A Quantum Chemical Study (2016-10-01)
Design, synthesis and biological evaluation of 5-benzylidene-2-iminothiazolidin-4-ones as selective GSK-3β inhibitors (2016-10-04)
A Metal and Base-Free Chemoselective Primary Amination of Boronic Acids Using Cyanamidyl/Arylcyanamidyl Radical as Aminating Species: Synthesis and Mechanistic Studies by Density Functional Theory (2016-06-17)
Molecular dynamics simulation studies of GSK-3β ATP competitive inhibitors: understanding the factors contributing to selectivity (2015-12-02)
Design, Synthesis, and Structural Analysis of Divalent NI Compounds and Identification of a New Electron-Donating Ligand (2016-01-18)
Mechanism of the Paal-Knorr reaction: the importance of water mediated hemialcohol pathway (2015-01-01)
Importance of Cytochromes in Cyclization Reactions: Quantum Chemical Study on a Model Reaction of Proguanil to Cycloguanil (2014-10-30)
Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme (2014-01-15)
Design of Glycogen Synthase Kinase-3 Inhibitors: An Overview on Recent Advancements (2013-08-01)

المواد التدريسية

Organic Chemistry I (PHC 103)
Organic Chemistry II (PHC 122)
Medicinal Chemistry I (PHC 225)

روابط المواقع الالكترونية الرسمية التعليمية السعودية تنتهي بـ

edu.sa

المواقع الالكترونية الحكومية تستخدم بروتوكول HTTPS للتشفير و الأمان.

أعضاء هيئة التدريس

المحتوى

منهاج ال عارفين محمد جاويد

أستاذ مشارك

كلية الصيدلة،

قسم دكتور صيدلي

البيانات الشخصية

المؤهلات العلمية

الاهتمامات البحثية

الأبحاث المنشورة

المواد التدريسية

روابط المواقع الالكترونية الرسمية التعليمية السعودية تنتهي بـedu.sa

المواقع الالكترونية الحكومية تستخدم بروتوكول HTTPS للتشفير و الأمان.

أعضاء هيئة التدريس

المحتوى

منهاج ال عارفين محمد جاويد

أستاذ مشارك

كلية الصيدلة،

قسم دكتور صيدلي

البيانات الشخصية

المؤهلات العلمية

الاهتمامات البحثية

الأبحاث المنشورة

المواد التدريسية

روابط المواقع الالكترونية الرسمية التعليمية السعودية تنتهي بـ

edu.sa