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Faculty members

Content

Inside a building, a man dressed in a traditional white uniform with a red and white Saudi shemagh wears a neutral expression as if he were taking a picture of a faculty file at Qassim University.
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Minhajul MohammadJawed AbdulMannan Arfeen

Associate Professor
College of Pharmacy,
Pharm.D Department

Personal data

  • 14623
  • M.Arfeen@qu.edu.sa
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    Scientific qualifications

    • B. Sc. Chemistry and Botany
    • B. Pharm.
    • M. S. (Pharm.) Medicinal Chemistry
    • Ph. D. Medicinal Chemistry

    Research interests

    • Selective Human TopoIIα topoisomerase inhibitors
    • Identification of new Carbocyclic, N-heterocyclic carbenes and r-N-heterocyclic carbenes

    Published research

    • Design, classification, and adverse effects of NSAIDs: A review on recent advancements (2024-01-01)
    • Design, synthesis, and biological evaluation of 5-benzylidene-2-iminothiazolidin-4-ones as selective GSK-3β inhibitors (2016-01-01)
    • Molecular dynamics simulation studies of GSK-3β ATP competitive inhibitors: understanding the factors contributing to selectivity (2015-01-01)
    • Dihydropyridines as potential α-amylase and α-glucosidase inhibitors: synthesis, in vitro and in silico studies (2020-01-01)
    • Design of glycogen synthase kinase-3 inhibitors: an overview on recent advancements (2013-01-01)
    • Design, Synthesis, and Structural Analysis of Divalent NI Compounds and Identification of a New Electron‐Donating Ligand (2016-01-01)
    • Mechanism of the Paal–Knorr reaction: the importance of water mediated hemialcohol pathway (2015-01-01)
    • Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme (2014-01-01)
    • Can Remote N‐Heterocyclic Carbenes Coordinate with Main Group Elements? Synthesis, Structure, and Quantum Chemical Analysis of N+‐Centered Complexes (2018-01-01)
    • Design, synthesis, and biological evaluation of 4-aminoquinoline-guanylthiourea derivatives as antimalarial agents (2019-01-01)
    • Importance of cytochromes in cyclization reactions: quantum chemical study on a model reaction of proguanil to cycloguanil (2014-01-01)
    • A metal and base-free chemoselective primary amination of boronic acids using cyanamidyl/arylcyanamidyl radical as aminating species: synthesis and mechanistic studies by … (2016-01-01)
    • Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in vivo and molecular modelling studies (2017-01-01)
    • Sukkari Dates Seed Improves Type-2 Diabetes Mellitus-Induced Memory Impairment by Reducing Blood Glucose Levels and Enhancing Brain Cholinergic Transmission: In Vivo and … (2022-01-01)
    • Neuroprotective effect of methanolic Ajwa seed extract on lipopolysaccharide-induced memory dysfunction and neuroinflammation: In vivo, molecular docking, and dynamics studies (2023-01-01)
    • Carbene →N+ Coordination Bonds in Drugs: A Quantum Chemical Study (2016-01-01)
    • Piracetam as a therapeutic agent for doxorubicin-induced cognitive deficits by enhancing cholinergic functions and reducing neuronal inflammation, apoptosis, and oxidative stress (2022-01-01)
    • Levetiracetam Ameliorates Doxorubicin-Induced Chemobrain by Enhancing Cholinergic Transmission and Reducing Neuroinflammation Using an Experimental Rat Model and Molecular... (2022-01-01)
    • Phytochemical profiling, molecular docking, and in vitro anti-hepatocellular carcinoid bioactivity of Suaeda vermiculata extracts (2022-01-01)
    • Aqueous Ajwa dates seeds extract improves memory impairment in type-2 diabetes mellitus rats by reducing blood glucose levels and enhancing brain cholinergic transmission (2022-01-01)
    • Divalent Ni Compounds: Identifying New Carbocyclic Carbenes to Design Nitrones Using Quantum Chemical Methods (2020-01-01)
    • Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial Functions in Mice (2021-01-01)
    • In vivo and computational studies on sitagliptin’s neuroprotective role in type 2 diabetes mellitus: Implications for Alzheimer’s disease (2024-01-01)
    • Electronic and Ligation Properties of Carbocyclic Carbenes: A Theoretical Investigation (2019-01-01)
    • Betahistine’s neuroprotective actions against lipopolysaccharide-induced neurotoxicity: Insights from experimental and computational studies (2024-01-01)
    • Ciproxifan ameliorates lipopolysaccharide-induced memory deficits by modulating cholinergic transmission in the mouse brain. (2022-01-01)
    • Assessing the influence of intermittent alcohol access on acrylamide-induced neuronal toxicity in an experimental rat model (2024-01-01)
    • Montelukast's potential as a neuroprotective agent against acrylamide-induced neurotoxicity: In vivo and computational modeling (2025-01-01)
    • Multipotent effect of clozapine on lipopolysaccharide-induced acetylcholinesterase, cyclooxygenase-2, 5-lipoxygenase, and caspase-3: In vivo and molecular modeling studies (2025-01-01)
    • Sertraline as a Multi-Target Modulator of AChE, COX-2, BACE-1, and GSK-3β: Computational and In Vivo Studies (2024-01-01)
    • Acrylamide exposure exacerbates type 2 diabetes-induced neurotoxicity: an integrated neurobehavioral and molecular investigation (2026-01-01)
    • Screening of Polyphenolic compounds to identify dual inhibitors against Glycogen Synthase 3β and Acetylcholinesterase for the treatment of Alzheimer's Diseases (2024-01-01)
    • Multi targeted ligands for potential inhibition of dipeptidyl peptidase 4, acetylcholinesterase and cyclooxygenase 2 (2024-01-01)
    • Aqueous Extract from Sukkari Date Seeds Attenuates Neuroinflammation Induced by Type-2 Diabetes in Rats (2022-01-01)
    • Neuroprotective Effect of Aqueous Extract of Ajwa Seeds via Anti-Inflammatory Pathways in Type-2 Diabetic-Induced Rats (2022-01-01)
    • Modular Approach to In Silico Antiviral Multitarget Inhibitors: Molecular Docking, Dynamics, Principal Component Analysis, Clustering, and Energy Landscape (2026-01-01)
    • Levetiracetam mitigates doxorubicin-induced oxidative stress associated with cognitive impairments and neurodegeneration in experimental rats: In vivo and molecular modeling … (2024-01-01)
    • NEUROPROTECTIVE EFFECTS OF HISTAMINE H3 RECEPTOR LIGANDS CIPROXIFAN AND CLOBENPROPIT THROUGH ANTIAPOPTOTIC AND ANTIOXIDANT MECHANISMS: EVIDENCE FROM IN VIVO AND COMPUTATIONAL … (2026-01-01)
    • Aryloxyethylamines Chalcones as Potential β3 AR Binders: Synthesis, In Vivo Antidiabetic and Molecular Modeling Studies (2026-01-01)
    • Neuroprotective Effect of Clobenpropit in Lipopolysaccharide-Induced Mice via Enhancing Cholinergic Transmission (2022-01-01)
    • Ciproxifan Attenuates Lipopolysaccharide-Induced Neuroinflammation and Mitochondrial Dysfunctions in Mouse Brain (2022-01-01)
    • Recent Advances in the Synthesis of Peptides and Proteins (2017-01-01)
    • NBO 2015–1517 references Compiled by Ariel Andrea on 1/07/2016 (2015-01-01)
    • Design and Synthesis of Substrate Competitive Inhibitors: Towards Selective GSK-3β Inhibition (2026-01-01)
    • Rational Design of 2-Imino-5-(2-oxo-2-phenylethyl) thiazolidin-4-one derivatives as Substrate Competitive Inhibitors of GSK-3 (2026-01-01)

    Teaching materials

    • Organic Chemistry I (PHC 103)
    • Organic Chemistry II (PHC 122)
    • Medicinal Chemistry I (PHC 225)

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