خالد سعد شارع الحربي - جامعة القصيم

موقع حكومي رسمي تابع لحكومة المملكة العربية السعودية كيف تتحقق

روابط المواقع الالكترونية الرسمية التعليمية السعودية تنتهي بـ

edu.sa

جميع روابط المواقع الرسمية التعليمية التابعة للجهات الحكومية في المملكة العربية السعودية تنتهي بـ .edu.sa

المواقع الالكترونية الحكومية تستخدم بروتوكول HTTPS للتشفير و الأمان.

المواقع الالكترونية الآمنة في المملكة العربية السعودية تستخدم بروتوكول HTTPS للتشفير.

مسجل لدى هيئة الحكومة الرقمية برقم: 20260416249

أعضاء هيئة التدريس

خالد سعد شارع الحربي

أستاذ

كلية الصيدلة،

قسم علم الأدوية والسموم

البيانات الشخصية

المؤهلات العلمية

الاهتمامات البحثية

الأبحاث المنشورة

In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways (2025-01-24)
Effect of sakuranetin against cyclophosphamide-induced immunodeficiency mice: role of IFN-γ/TNF-α/IgG/IgM/interleukins (2025-03-08)
Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling (2025-07-26)
p-Cymene inhibits pro-fibrotic and inflammatory mediators to prevent hepatic dysfunction (2025-04-15)
Effects of a Rosiridin against Rotenone-induced Rats Model of Parkinson's Disease: <i>In-vivo</i> Study and <i>in silico</i> Molecular Modeling (2025-01-01)
Cubebin Attenuates Methamphetamine-Induced Neurotoxicity Through CREB/BDNF/Caspase-3 Signaling: In Vivo and In Silico Study (2025-08-31)
Therapeutic Potential of Lacidipine against 3-Nitropropionic Acid Induced Huntington's Disease : Based on Molecular Docking, Anti-Inflammatory and Neuroprotective Effects (2025-10-01)
EGF-functionalized lipid-polymer hybrid nanoparticles of 5-fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma (2021-11-25)
Biocompatible phospholipid-based nanovesicular drug delivery system of ketoprofen: Systematic development, optimization, and preclinical evaluation (2022-03-19)
Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3/NF-κB/ Bcl-2 signaling pathways in rats and in silico study (2024-12-02)
Caffeic Acid Loaded Lipid Polymer Hybrid Nanoparticles: Ex Vivo and Pre-clinical Evaluation Against Liver Cirrhosis (2022-09-01)
Implications of Solid Lipid Nanoparticles of Ganoderic Acid for the Treatment and Management of Hepatocellular Carcinoma (2020-05-30)
Promises of phytochemical based nano drug delivery systems in the management of cancer (2021-11-16)
Development of solid lipid nanoparticle as carrier of pioglitazone for amplification of oral efficacy: Formulation design optimization, <i>in</i>-<i>vitro</i> characterization and <i>in</i>-<i>vivo</i> biological evaluation (2020-06-01)
Diosmin-loaded solid nanoparticles as nano-antioxidant therapy for management of hepatocellular carcinoma: QbD-based optimization, <i>in vitro</i> and in vivo evaluation (2021-02-10)
Implications of phospholipid-based nanomixed micelles of olmesartan medoxomil with enhanced lymphatic drug targeting ability and systemic bioavailability (2021-01-22)
Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma (2021-08-07)
Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-? signaling in rotenone induced parkinsonism in rats (2022-12-21)
Oxyphenbutazone ameliorates carfilzomib induced cardiotoxicity in rats via inhibition of oxidative free radical burst and NF-xB/IxB-α pathway (2023-12-22)
Formulation and characterization of polymeric nanoparticle of Rivastigmine for effective management of Alzheimer's disease (2024-03-28)
Exploring GAS5's impact on prostate cancer: Recent discoveries and emerging paradigms (2023-10-12)
GAS5: A pivotal lncRNA in diabetes mellitus pathogenesis and management (2023-11-27)
Apoptosis-driven synergistic anti-cancer efficacy of ethyl acetate extract of<i> Memecylon</i><i> sisparense</i> Gamble leaves and doxorubicin in in-vitro and in-vivo models of triple-negative breast cancer (2024-01-03)
The ncRNA-TGF-β axis: Unveiling new frontiers in colorectal cancer research (2024-01-23)
Noncoding RNAs in hepatitis: Unraveling the apoptotic pathways (2024-02-06)
Non-coding RNAs as therapeutic targets in Parkinson's Disease: A focus on dopamine (2024-10-11)
Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma (2022-03-22)
Systematic Development of Solid Lipid Nanoparticles of Abiraterone Acetate with Improved Oral Bioavailability and Anticancer Activity for Prostate Carcinoma Treatment (2022-05-09)
Formulation of amorphous ternary solid dispersions of dapagliflozin using PEG 6000 and Poloxamer 188: solid-state characterization,<i>ex vivo</i>study, and molecular simulation assessment (2020-08-04)
Formulation of Chitosan Polymeric Vesicles of Ciprofloxacin for Ocular Delivery: Box-Behnken Optimization, <i>In Vitro</i> Characterization, HET-CAM Irritation, and Antimicrobial Assessment (2020-06-05)
Nanotherapeutic systems for delivering cancer vaccines: recent advances (2020-06-01)
Anti-Huntington's Effect of Rosiridin via Oxidative Stress/AchE Inhibition and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels against 3-Nitropropionic Acid in Rodents (2022-08-01)
Europinidin Mitigates 3-NPA-Induced Huntington's Disease Symptoms in Rats: A Comprehensive Analysis of Oxidative Stress, Mitochondrial Enzyme Complex Activity, Pro-Inflammatory Markers and Neurotransmitter Alterations (2024-03-01)
Rosiridin Protects Against Aluminum Chloride-Induced Memory Impairment via Modulation of BDNF/NFκB/PI3K/Akt Pathway in Rats (2024-11-01)
Barbaloin Protects Pentylenetetrazol-Induced Cognitive Deficits in Rodents via Modulation of Neurotransmitters and Inhibition of Oxidative-Free-Radicals-Led Inflammation (2024-06-01)
Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity (2020-02-01)
Europinidin Enhances Healing through Modulating Antioxidant Processes in Experimentally Induced-Stomach Ulcer Condition (2022-01-01)
Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress Leaded Caspase-3/9 and TNF-α Signaling Pathways (2022-09-01)
Oxyphenbutazone improves memory and learning impairments in LPS-induced neurotoxicity via modulating TGF-β/NF-κB/IκB-α pathways: In silico and in vivo study (2026-01-20)
Neuroprotective effects of aegeline against LPS-induced memory dysfunction: involvement of hippocampal cholinergic/proinflammatory cytokines receptor modulation and insilico insight (2026-01-07)
Marmelosin Protects Against Metabolic Disturbances in High-Fat Diet and Streptozotocin-Induced Diabetes (2025-01-01)
Aloesin alleviates imiquimod-induced psoriasis in dermal layers through inhibition of interleukins and NF-κB signaling pathways (2025-12-01)
Public Perception of Renewable Energy as a Fossil Fuel Alternative in Saudi Arabia: A Case Study from Riyadh (2026-04-12)
Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3/NF-κB/Bcl-2 signaling pathways in rats and in silico study (vol. 398, pg. 5895, 2024) (2026-03-11)
A Hybrid Convolutional-Transformer Approach for Accurate Electroencephalography (EEG)-Based Parkinson's Disease Detection (2025-05-28)
Exploring the Effects of Renewable Energy, Energy Consumption, and Industrial Growth on Saudi Arabia's Environmental Footprint: An Autoregressive Distributed Lag Analysis (2024-12-01)
Conceptual Design for an Advanced High Field 30 MeV Superconducting Cyclotron for Medical Isotopes Production (2024-01-01)
A Magnet Design of an Advanced High-Field Superconducting Cyclotron for Medical Isotope Production (2024-09-15)
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration (2024-01-01)
Innovative pilot plant capacitive deionization for desalination brackish water (2024-02-01)
Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation (2023-09-27)
Promises of Molecular Pharmaceutics in the Development of Novel Drug Delivery Formulations (2023-01-01)
Role of Flavonoids in Management of Various Biological Targets in Alzheimer's Disease: Evidence from Preclinical to Clinical Studies (2023-01-01)
Detection of Circulating Tumor Cells and Epithelial Progenitor Cells: A Comprehensive Study (2023-01-01)
Revealing genetic links of Type 2 diabetes that lead to the development of Alzheimer?s disease (2023-01-21)
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, <i>in vitro</i>, and <i>in silico</i> mechanistic investigations (2023-01-10)
Polysaccharide-Based Nanomedicines Targeting Lung Cancer (2022-12-01)
PI3K/Akt/mTOR Pathways Inhibitors with Potential Prospects in Non-Small-Cell Lung Cancer (2022-01-01)
Gingerol, a Natural Antioxidant, Attenuates Hyperglycemia and Downstream Complications (2022-12-01)
Barriers and facilitators of childhood COVID-19 vaccination among parents: A systematic review (2022-11-24)
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction (2022-08-25)
Formulation of intranasal surface engineered nanostructured lipid carriers of rotigotine: Full factorial design optimization, in vitro characterization, and pharmacokinetic evaluation (2022-10-01)
Oligonucleotides: A novel area of interest for drug delivery in neurodegenerative diseases (2022-10-12)
Effects of the Anthocyanin Hirsutidin on Gastric Ulcers: Improved Healing through Antioxidant Mechanisms (2022-10-10)
A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age-related and kidney diseases (2022-10-21)
An overview of epithelial growth factor receptor (EGFR) inhibitors in cancer therapy (2022-08-27)
Therapeutic approaches of nutraceuticals in the prevention of Alzheimer's disease (2022-09-28)
Potential role of nutraceuticals via targeting a Wnt/β-catenin and NF-κB pathway in treatment of osteoarthritis (2022-09-27)
Role of Medicinal plant-derived Nutraceuticals as a potential target for the treatment of breast cancer (2022-09-19)
Molecular explanation of Wnt/βcatenin antagonist pyrvinium mediated calcium equilibrium changes in aging cardiovascular disorders (2022-09-15)
Rosinidin Protects Streptozotocin-Induced Memory Impairment-Activated Neurotoxicity by Suppressing Oxidative Stress and Inflammatory Mediators in Rats (2022-08-01)
The therapeutic role of nutraceuticals targeting the Nrf2/HO-1 signaling pathway in liver cancer (2022-08-09)
Molecular exploration of hidden pleiotropic activities of azoles on dermatophytes in human<i> tinea</i><i> corporis</i> infection (2022-07-28)
Formulation and Evaluation of Moxifloxacin Loaded Bilosomes In-Situ Gel: Optimization to Antibacterial Evaluation (2022-07-01)
A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration (2022-08-25)
Sodium alginate based drug delivery in management of breast cancer (2022-06-07)
Pharmacological evaluation of cardioprotective potential of <i>Berberis orthobotrys</i> Bien.ex Aitch. (2022-01-01)
Cardioprotective potential of <i>Thymus linearis</i> Benth (2022-01-01)
Synthesis and Characterization of Antibiotic-Loaded Biodegradable Citrate Functionalized Mesoporous Hydroxyapatite Nanocarriers as an Alternative Treatment for Bone Infections (2022-05-01)
Impact of highly phospholipid-containing lipid nanocarriers on oral bioavailability and pharmacodynamics performance of genistein (2022-05-20)
Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre / Pro-biotics in manipulating microflora (2022-03-28)
Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using breast cancer cell line (2022-01-11)
Nuclear factor-kappa B (NF-ΚB) inhibition as a therapeutic target for plant nutraceuticals in mitigating inflammatory lung diseases (2022-02-01)
The potential protective effect of the <i>Polygonum hydropiper</i> L against the development of fructose-induced oxidative stress and metabolic disorders in male Sprague-Dawely rats (2021-06-22)
Bioactive Luteolin Entrapped Chitosan-PLGA Nanoparticles: Formulation Optimization to In-Vivo Preclinical Evaluation (2022-02-07)
Anti-Huntington's Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action (2022-01-04)
6-Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α, IL-1β, and BDNF: Insight into the Mechanism (2021-12-28)
Therapeutic potential of nanoemulsions as feasible wagons for targeting Alzheimer's disease (2021-11-29)
Formulation of Genistein-HP β Cyclodextrin-Poloxamer 188 Ternary Inclusion Complex: Solubility to Cytotoxicity Assessment (2021-12-01)
Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases (2021-10-15)
A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer (2021-11-06)
Development of Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization, In-Vitro, Ex-Vivo, and In-Vivo Evaluation (2021-11-01)
Ethyl-acetate extract of tara mira<i> (Eruca</i><i> sativa)</i> alleviates the inflammation and rheumatoid arthritis in rats (2021-09-01)
Formulation of Chitosan-Coated Piperine NLCs: Optimization, <i>In Vitro</i> Characterization, and <i>In Vivo</i> Preclinical Assessment (2021-08-31)
Formulation of carteolol chitosomes for ocular delivery: formulation optimization, <i>ex-vivo</i> permeation, and ocular toxicity examination (2021-08-02)
Nuclear factor-kappa B and its role in inflammatory lung disease (2021-06-30)
Role of Epithelial-to-Mesenchymal Transition Markers in Different Stages of Endometriosis: Expression of the <i>Snail</i>, <i>Slug</i>, <i>ZEB1</i>, and <i>Twist</i> Genes (2021-01-01)
Chitosan-ethyl cellulose microspheres of domperidone for nasal delivery: Preparation, in-vitro characterization, in-vivo study for pharmacokinetic evaluation and bioavailability enhancement (2021-04-20)
Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity (2021-03-01)
Methanolic extract of <i>Cucumis melo</i> attenuates ethylene glycol-induced nephrolithiasis in Wistar rats (2021-04-09)
Nanomedicine in treatment of breast cancer ? A challenge to conventional therapy (2021-03-02)
Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems (2021-03-02)
Functionalized mesoporous silica nanoparticles in anticancer therapeutics (2021-03-02)
Simultaneous analysis of several antihypertensive drugs in different combinations: Application for determination of drug degradation products and process impurities (2021-04-02)
Identification of <i>N</i>-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities (2021-03-25)
Calcium sensing receptor hyperactivation through viral envelop protein E of SARS CoV2: A novel target for cardio-renal damage in COVID-19 infection (2021-03-09)
Novel nanotechnology approaches for diagnosis and therapy of breast, ovarian and cervical cancer in female: A review (2021-02-10)
RETRACTED: Appraisal of the Antiarthritic Potential of Prazosin via Inhibition of Proinflammatory Cytokine TNF-α: A Key Player in Rheumatoid Arthritis (2021-01-26)
Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity (2020-12-01)
Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage (2020-11-01)
Effects of berberine on intestinal flora of Non-alcoholic fatty liver induced by High-fat diet through 16S rRNA gene segmentation (2020-07-01)
Phytochemical analysis and reappraisal of diuretic activity of <i>Delphinium brunonianum</i> Royle and its mode of action in experimental rats (2020-07-01)
Study on vascular mechanisms underlying the hypotensive effect of <i>Sorghum halepense</i> (L.) Pers (2020-09-01)
Blood pressure lowering effects of <i>Ranunculus scleratus</i> Linn. in normal and fructose induced hypertensive rats and estimation of underlying mechanisms (2020-09-01)
Beta-catenin non-canonical pathway: A potential target for inflammatory and hyperproliferative state via expression of transglutaminase 2 in psoriatic skin keratinocyte (2020-09-07)
MG132 inhibits the expression of PBX3 through miRNAs by targeting Argonaute2 in hepatoma cells (2020-08-01)
Original Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca 2+-channel (2020-06-01)
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and <i>in silico</i> insights (2020-07-01)
Nucleic acid-loaded lipid-polymer nanohybrids as novel nanotherapeutics in anticancer therapy (2020-05-07)
Pharmacological appraisal of ligustrazine based cyclohexanone analogs as inhibitors of inflammatory markers (2020-04-30)
Superbranched polyglycerol nanostructures as drug delivery and theranostics tools for cancer treatment (2020-04-01)
Nasal Mucoadhesive Microspheres of Lercanidipine with Improved Systemic Bioavailability and Antihypertensive Activity (2020-03-24)
BBD-Based Development of Itraconazole Loaded Nanostructured Lipid Carrier for Topical Delivery: In Vitro Evaluation and Antimicrobial Assessment (2020-01-06)
Development of novel dapagliflozin loaded solid self-nanoemulsifying oral delivery system: Physiochemical characterization and <i>in vivo</i> antidiabetic activity (2019-12-01)
Protective Effect of RIVA Against Sunitinib-Induced Cardiotoxicity by Inhibiting Oxidative Stress-Mediated Inflammation: Probable Role of TGF-β and Smad Signaling (2019-11-06)
Non-Overparametrized Adaptive Backstepping Control of PWM DC-DC Non-Inverting Buck-Boost Power Converter (2019-01-01)
Stabilization Of SPMS Wind Generator With Boost Converter Using Backstepping Approach (2018-01-01)
Adaptive Backstepping Control of PWM DC-DC Boost Power Converter Considering Parasitic Elements Effect (2018-01-01)
Nanocolloidal lipidic carriers of olmesartan medoxomil surface-tailored with Concavalin-A for lectin receptor targeting (2018-12-01)
Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma (2019-01-01)
Morin-mediated regulation of apoptosis-autophagy crosstalk in Cancer: molecular mechanisms, preclinical evidence, and translational challenges (2026-06-19)
Multi-omics biomarkers in cadmium-related lung toxicity and carcinogenesis (2026-04-15)
Electrochemical biosensors for MMP-9 in hepatitis B liver inflammation (2025-12-01)
Effect of Tirzepatide on Cisplatin and Doxorubicin-Induced Cardiotoxicity and Nephrotoxicity (2025-01-01)
Silencing of tissue factor by antisense deoxyoligonucleotide mitigates thioacetamide-induced liver injury (2020-05-20)
The use of sectional matrix in direct restoration of a structurally compromised posterior tooth: a clinical technique (2019-10-01)
<i>Nigella sativa</i> oil alleviates doxorubicin-induced cardiomyopathy and neurobehavioral changes in mice:<i> In vivo </i>and <i>in-silico</i> study (2022-07-01)
An insight into the implications of estrogen deficiency and transforming growth factor β in antiepileptic drugs-induced bone loss (2021-07-08)
Three 'D's: Design approach, dimensional printing, and drug delivery systems as promising tools in healthcare applications (2021-11-19)
Lipid/polymer-based nanocomplexes in nucleic acid delivery as cancer vaccines (2021-08-27)
Biocompatible Polymeric Nanoparticles for Effective Codelivery of Tamoxifen with Ganoderic Acid A: Systematic Approach for Improved Breast Cancer Therapeutics (2022-07-25)
Autologous Stem Cell Transplant in Hodgkin's and Non-Hodgkin's Lymphoma, Multiple Myeloma, and AL Amyloidosis (2023-12-01)
Nuclear factor-kappa B and its role in inflammatory lung disease (2021-01-01)
Nanomedicine in treatment of breast cancer–A challenge to conventional therapy (2021-01-01)
Functionalized mesoporous silica nanoparticles in anticancer therapeutics (2021-01-01)
Sodium alginate based drug delivery in management of breast cancer (2022-01-01)
A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer (2022-01-01)
Polysaccharide-based nanomedicines targeting lung cancer (2022-01-01)
Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma (2019-01-01)
Gene therapy approach with an emphasis on growth factors: theoretical and clinical outcomes in neurodegenerative diseases (2022-01-01)
Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment (2021-01-01)
Nuclear factor-kappa B (NF-κB) inhibition as a therapeutic target for plant nutraceuticals in mitigating inflammatory lung diseases (2022-01-01)
Gingerol, a natural antioxidant, attenuates hyperglycemia and downstream complications (2022-01-01)
Role of medicinal plant‐derived nutraceuticals as a potential target for the treatment of breast cancer (2022-01-01)
An overview of epithelial growth factor receptor (EGFR) inhibitors in cancer therapy (2022-01-01)
Formulation and evaluation of moxifloxacin loaded bilosomes in-situ gel: optimization to antibacterial evaluation (2022-01-01)
Comparative effectiveness of EDTA and citric acid assisted phytoremediation of Ni contaminated soil by using canola (Brassica napus) (2022-01-01)
Formulation of intranasal surface engineered nanostructured lipid carriers of rotigotine: Full factorial design optimization, in vitro characterization, and pharmacokinetic … (2022-01-01)
BBD-based development of itraconazole loaded nanostructured lipid carrier for topical delivery: in vitro evaluation and antimicrobial assessment (2021-01-01)
Formulation of Chitosan Polymeric Vesicles of Ciprofloxacin for Ocular Delivery: Box-Behnken Optimization, In Vitro Characterization, HET-CAM Irritation, and … (2020-01-01)
Design, click conventional and microwave syntheses, DNA binding, docking and anticancer studies of benzotriazole-1, 2, 3-triazole molecular hybrids with different pharmacophores (2021-01-01)
Development of solid lipid nanoparticle as carrier of pioglitazone for amplification of oral efficacy: formulation design optimization, in-vitro characterization and in-vivo … (2020-01-01)
Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems (2021-01-01)
Novel 1, 2, 4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity (2020-01-01)
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights (2020-01-01)
Design, synthesis and biological evaluation of new HDAC1 and HDAC2 inhibitors endowed with ligustrazine as a novel cap moiety (2020-01-01)
Exploring satisfaction level among outpatients regarding pharmacy facilities and services in the Kingdom of Saudi Arabia; a large regional analysis (2021-01-01)
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico … (2023-01-01)
Therapeutic potential of nanoemulsions as feasible wagons for targeting Alzheimer’s disease (2021-01-01)
The therapeutic role of nutraceuticals targeting the Nrf2/HO‐1 signaling pathway in liver cancer (2022-01-01)
Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre/Pro-biotics in manipulating microflora (2022-01-01)
Promises of phytochemical based nano drug delivery systems in the management of cancer (2022-01-01)
Long-acting paliperidone parenteral formulations based on polycaprolactone nanoparticles; the influence of stabilizer and chitosan on in vitro release, protein adsorption, and … (2020-01-01)
Systematic development of solid lipid nanoparticles of abiraterone acetate with improved oral bioavailability and anticancer activity for prostate carcinoma treatment (2022-01-01)
PI3K/Akt/mTOR pathways inhibitors with potential prospects in non-small-cell lung cancer (2022-01-01)
Development of novel dapagliflozin loaded solid self-nanoemulsifying oral delivery system: Physiochemical characterization and in vivo antidiabetic activity (2019-01-01)
Rosiridin attenuates scopolamine-induced cognitive impairments in rats via inhibition of oxidative and nitrative stress leaded caspase-3/9 and TNF-α signaling pathways (2022-01-01)
Nucleic acid-loaded lipid-polymer nanohybrids as novel nanotherapeutics in anticancer therapy (2020-01-01)
Lipid/polymer-based nanocomplexes in nucleic acid delivery as cancer vaccines (2021-01-01)
Superbranched polyglycerol nanostructures as drug delivery and theranostics tools for cancer treatment (2021-01-01)
Nanotherapeutic systems for delivering cancer vaccines: Recent advances (2020-01-01)
A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age‐related and kidney diseases (2022-01-01)
6‑Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α … (2022-01-01)
Development of piperine-loaded solid self-nanoemulsifying drug delivery system: optimization, in-vitro, ex-vivo, and in-vivo evaluation (2021-01-01)
Therapeutic approaches of nutraceuticals in the prevention of Alzheimer's disease (2022-01-01)
Barriers and facilitators of childhood COVID-19 vaccination among parents: A systematic review (2022-01-01)
Formulation of genistein-hp β cyclodextrin-poloxamer 188 ternary inclusion complex: Solubility to cytotoxicity assessment (2021-01-01)
Role of Epithelial-to-Mesenchymal Transition Markers in Different Stages of Endometriosis: Expression of the Snail, Slug, ZEB1, and Twist Genes (2021-01-01)
Identification of N-phenyl-2-(phenylsulfonyl) acetamides/propanamides as new SLC-0111 analogues: synthesis and evaluation of the carbonic anhydrase inhibitory activities (2021-01-01)
Chitosan-ethyl cellulose microspheres of domperidone for nasal delivery: Preparation, in-vitro characterization, in-vivo study for pharmacokinetic evaluation and … (2021-01-01)
Nanocarriers-loaded with natural actives as newer therapeutic interventions for treatment of hepatocellular carcinoma (2021-01-01)
Novel nanotechnology approaches for diagnosis and therapy of breast, ovarian and cervical cancer in female: A review (2021-01-01)
Formulation of Chitosan-Coated Piperine NLCs: Optimization, In Vitro Characterization, and In Vivo Preclinical Assessment: Formulation of Chitosan-Coated … (2021-01-01)
Formulation and characterization of polymeric nanoparticle of Rivastigmine for effective management of Alzheimer’s disease (2024-01-01)
Evaluation of anti-cancer effects of carnosine and melittin-loaded niosomes in MCF-7 and MDA-MB-231 breast cancer cells (2023-01-01)
Mucoadhesive in situ rectal gel loaded with rifampicin: Strategy to improve bioavailability and alleviate liver toxicity (2021-01-01)
Anaesthesia-induced changes in genomic expression leading to neurodegeneration (2024-01-01)
Beta‐catenin non‐canonical pathway: A potential target for inflammatory and hyperproliferative state via expression of transglutaminase 2 in psoriatic skin keratinocyte (2020-01-01)
Protective effect of RIVA against sunitinib-induced cardiotoxicity by inhibiting oxidative stress-mediated inflammation: probable role of TGF-β and Smad signaling (2020-01-01)
Potential role of nutraceuticals via targeting a Wnt/β‐catenin and NF‐κB pathway in treatment of osteoarthritis (2022-01-01)
Implications of solid lipid nanoparticles of ganoderic acid for the treatment and management of hepatocellular carcinoma (2021-01-01)
Role of rivaroxaban in sunitinib-induced renal injuries via inhibition of oxidative stress-induced apoptosis and inflammation through the tissue nacrosis factor-α induced … (2020-01-01)
EGF‐functionalized lipid–polymer hybrid nanoparticles of 5‐fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma (2022-01-01)
Hispolon-loaded liquid crystalline nanoparticles: Development, stability, in vitro delivery profile, and assessment of hepatoprotective activity in hepatocellular carcinoma (2022-01-01)
Nasal mucoadhesive microspheres of lercanidipine with improved systemic bioavailability and antihypertensive activity (2021-01-01)
Diosmin-loaded solid nanoparticles as nano-antioxidant therapy for management of hepatocellular carcinoma: QbD-based optimization, in vitro and in vivo evaluation (2021-01-01)
Detection of circulating tumor cells and epithelial progenitor cells: A comprehensive study (2023-01-01)
Anti-Huntington’s effect of butin in 3-nitropropionic acid-treated rats: possible mechanism of action (2022-01-01)
A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration (2022-01-01)
Formulation of ternary genistein β-cyclodextrin inclusion complex: In vitro characterization and cytotoxicity assessment using breast cancer cell line (2022-01-01)
Complete Blood-count-based Inflammatory Score (CBCS) of COVID-19 Patients at Tertiary Care Center. (2021-01-01)
Nanocolloidal lipidic carriers of olmesartan medoxomil surface-tailored with Concavalin-A for lectin receptor targeting (2018-01-01)
Rosiridin protects against aluminum chloride-induced memory impairment via modulation of BDNF/NFκB/PI3K/Akt pathway in rats (2024-01-01)
Synthesis and characterization of antibiotic–loaded biodegradable citrate functionalized mesoporous hydroxyapatite nanocarriers as an alternative treatment for bone infections (2022-01-01)
Three ‘D’s: Design approach, dimensional printing, and drug delivery systems as promising tools in healthcare applications (2021-01-01)
Rosinidin protects streptozotocin-induced memory impairment-activated neurotoxicity by suppressing oxidative stress and inflammatory mediators in rats (2022-01-01)
6-Shogaol attenuated ethylene glycol and aluminium chloride induced urolithiasis and renal injuries in rodents (2021-01-01)
Effects of berberine on intestinal flora of non-alcoholic fatty liver induced by high-fat diet through 16S rRNA gene segmentation (2020-01-01)
Autologous stem cell transplant in hodgkin’s and non-hodgkin’s lymphoma, multiple myeloma, and al amyloidosis (2023-01-01)
Role of flavonoids in management of various biological targets in Alzheimer’s disease: evidence from preclinical to clinical studies (2023-01-01)
Dabigatran mitigates cisplatin-mediated nephrotoxicity through down regulation of thrombin pathway (2021-01-01)
Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats (2022-01-01)
Effects of the anthocyanin hirsutidin on gastric ulcers: improved healing through antioxidant mechanisms (2022-01-01)
Potential of natural bioactive compounds in management of diabetes: review of preclinical and clinical evidence (2021-01-01)
Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage (2020-01-01)
Pathophysiology and pathogenesis of inflammation (2023-01-01)
Bioactive luteolin entrapped chitosan-PLGA nanoparticles: formulation optimization to in-vivo preclinical evaluation (2023-01-01)
Formulation of carteolol chitosomes for ocular delivery: formulation optimization, ex-vivo permeation, and ocular toxicity examination (2021-01-01)
Formulation of amorphous ternary solid dispersions of dapagliflozin using PEG 6000 and Poloxamer 188: solid-state characterization, ex vivo study, and molecular … (2020-01-01)
GAS5: A pivotal lncRNA in diabetes mellitus pathogenesis and management (2024-01-01)
Anti-Huntington’s effect of Rosiridin via oxidative stress/ache Inhibition and modulation of succinate dehydrogenase, nitrite, and BDNF levels against 3-Nitropropionic acid in … (2022-01-01)
Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma (2021-01-01)
Europinidin mitigates 3-NPA-induced Huntington’s disease symptoms in rats: a comprehensive analysis of oxidative stress, mitochondrial enzyme complex activity, pro-inflammatory … (2024-01-01)
Revealing genetic links of type 2 diabetes that lead to the development of Alzheimer’s disease (2023-01-01)
Molecular explanation of Wnt/βcatenin antagonist pyrvinium mediated calcium equilibrium changes in aging cardiovascular disorders (2022-01-01)
Exploring GAS5's impact on prostate cancer: Recent discoveries and emerging paradigms (2023-01-01)
Impact of highly phospholipid-containing lipid nanocarriers on oral bioavailability and pharmacodynamics performance of genistein (2022-01-01)
Calcium sensing receptor hyperactivation through viral envelop protein E of SARS CoV2: A novel target for cardio‐renal damage in COVID‐19 infection (2021-01-01)
Anticonvulsant effects of desvenlafaxine on modulating brain monoamine and oxidative stress in mice (2021-01-01)
Protective effect of baicalein alone and losartan–baicalein combination therapy on doxorubicin-induced hepatotoxicity in rats (2020-01-01)
Oligonucleotides: A novel area of interest for drug delivery in neurodegenerative diseases (2022-01-01)
Implications of phospholipid-based nanomixed micelles of olmesartan medoxomil with enhanced lymphatic drug targeting ability and systemic bioavailability (2021-01-01)
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction (2022-01-01)
Simultaneous analysis of several antihypertensive drugs in different combinations: Application for determination of drug degradation products and process impurities (2021-01-01)
Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3/NF-κB/Bcl-2 signaling pathways in rats and in silico study (2025-01-01)
Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation (2023-01-01)
Biocompatible polymeric nanoparticles for effective codelivery of tamoxifen with ganoderic acid A: systematic approach for improved breast cancer therapeutics (2023-01-01)
Boswellic acid attenuates scopolamine-induced neurotoxicity and dementia in rats: possible mechanism of action (2021-01-01)
Silencing of tissue factor by antisense deoxyoligonucleotide mitigates thioacetamide-induced liver injury (2020-01-01)
Evaluation of ligustrazine-based synthetic compounds for their antiproliferative effects (2021-01-01)
Methanolic extract of Cucumis melo attenuates ethylene glycol-induced nephrolithiasis in Wistar rats (2021-01-01)
The prediabetes outcome at national guard primary health care centers in Riyadh, Saudi Arabia: retrospective chart review (2020-01-01)
Effect of sakuranetin against cyclophosphamide-induced immunodeficiency mice: role of IFN-γ/TNF-α/IgG/IgM/interleukins (2025-01-01)
Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling (2025-01-01)
Barbaloin protects pentylenetetrazol-induced cognitive deficits in rodents via modulation of neurotransmitters and inhibition of oxidative-free-radicals-led inflammation (2024-01-01)
The potential protective effect of the Polygonum hydropiper L against the development of fructose-induced oxidative stress and metabolic disorders in male … (2022-01-01)
An insight into the implications of estrogen deficiency and transforming growth factor β in antiepileptic drugs-induced bone loss (2021-01-01)
Dietary phytochemicals and their potential effects on diabetes mellitus 2 (2019-01-01)
Apoptosis-driven synergistic anti-cancer efficacy of ethyl acetate extract of Memecylon sisparense Gamble leaves and doxorubicin in in-vitro and in-vivo models of triple … (2024-01-01)
Molecular exploration of hidden pleiotropic activities of azoles on dermatophytes in human tinea corporis infection (2022-01-01)
Europinidin enhances healing through modulating antioxidant processes in Experimentally Induced-stomach Ulcer Condition (2022-01-01)
Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca2+-channel (2020-01-01)
Pharmacological appraisal of ligustrazine based cyclohexanone analogs as inhibitors of inflammatory markers (2020-01-01)
Effects of a Rosiridin against Rotenone-induced Rats Model of Parkinson's Disease: In-vivo Study and in silico Molecular Modeling (2025-01-01)
In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways (2025-01-01)
Effect of tirzepatide on cisplatin and doxorubicin-induced cardiotoxicity and nephrotoxicity (2025-01-01)
Anxiety, mindfulness and self-efficacy association among university healthcare specialties students in Al Qassim, Saudi Arabia: a cross-sectional study (2023-01-01)
Caffeic Acid Loaded Lipid Polymer Hybrid Nanoparticles: Ex Vivo and Pre-clinical Evaluation Against Liver Cirrhosis: Md. A. Barkat et al. (2023-01-01)
Synergism of CD28 Immune Molecule in Late Immunosuppressive Phase of COVID-19: Effectiveness in Vaccinated Individuals. (2023-01-01)
Fundamental aspects of targeted drug delivery (2021-01-01)
MG132 inhibits the expression of PBX3 through miRNAs by targeting Argonaute2 in hepatoma cells (2020-01-01)
Non-coding RNAs as therapeutic targets in Parkinson’s Disease: A focus on dopamine (2024-01-01)
Oxyphenbutazone ameliorates carfilzomib induced cardiotoxicity in rats via inhibition of oxidative free radical burst and NF-κB/IκB-α pathway (2024-01-01)
Biocompatible phospholipid‐based nanovesicular drug delivery system of ketoprofen: Systematic development, optimization, and preclinical evaluation (2023-01-01)
Hormone related cancer mechanistic and nanomedicines: challenges and prospects (2022-01-01)
Cardioprotective potential of Thymus linearis Benth (2022-01-01)
Biomarkers as targeted herbal drug discovery: a pharmacological approach to nanomedicines (2021-01-01)
Phytochemical analysis and reappraisal of diuretic activity of Delphinium brunonianum Royle and its mode of action in experimental rats. (2020-01-01)
Impact of COVID-19 on nephrology patients: a mechanistic outlook for pathogenesis of acute kidney injury (2020-01-01)
p-Cymene inhibits pro-fibrotic and inflammatory mediators to prevent hepatic dysfunction (2025-01-01)
Promises of molecular pharmaceutics in the development of novel drug delivery formulations (2023-01-01)
Nigella sativa oil alleviates doxorubicin-induced cardiomyopathy and neurobehavioral changes in mice: In vivo: and: in-silico: study (2022-01-01)
Microbiome in asthma (2022-01-01)
Hormone Related Cancer Mechanistic and Nanomedicines (2022-01-01)
Ethyl-acetate extract of tara mira (Eruca sativa) alleviates the inflammation and rheumatoid arthritis in rats. (2021-01-01)
Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity. Pharmaceutics 2021, 13, 336 (2021-01-01)
Blood pressure lowering effects of Ranunculus scleratus Linn. in normal and fructose induced hypertensive rats and estimation of underlying mechanisms. (2020-01-01)
Aloesin alleviates imiquimod-induced psoriasis in dermal layers through inhibition of interleukins and NF-κB signaling pathways (2025-01-01)
Electrochemical biosensors for MMP-9 in hepatitis B liver inflammation (2025-01-01)
Cubebin attenuates methamphetamine-induced neurotoxicity through CREB/BDNF/Caspase-3 signaling: in vivo and in silico study (2025-01-01)
Noncoding RNAs in hepatitis: Unraveling the apoptotic pathways (2024-01-01)
The ncRNA-TGF-β axis: unveiling new frontiers in colorectal cancer research (2024-01-01)
Phyto-actives and their targeted action in management of hepatocellular Carcinoma: scope of nanomedicine in its effective delivery (2022-01-01)
Bioactive-loaded Nanomedicine for the Management of Health and Disease (2022-01-01)
Pharmacological evaluation of cardioprotective potential of Berberis orthobotrys Bien. ex Aitch (2022-01-01)
Oxyphenbutazone improves memory and learning impairments in LPS-induced neurotoxicity via modulating TGF-β/NF-κB/IκB-α pathways: In silico and in vivo study (2026-01-01)
Effect of mercury on gut microbiome (2025-01-01)
Epigenetic Optimization in Chronic Obstructive Pulmonary Disease (COPD) (2023-01-01)
A cross-sectional survey: The “Saudi guidelines for the prevention and management of obesity”: Awareness and adaptation in Al-Qassim province (2022-01-01)
Post-traumatic Stress Disorders (PTSD) (2020-01-01)
Evaluation of effect of Acacia jacquemontii Benth. on blood pressure in normotensive and fructose induced hypertensive sprague dawley rats: An ethnopharmacological approach. (2020-01-01)
Study on vascular mechanisms underlying the hypotensive effect of Sorghum halepense (L.) Pers. (2020-01-01)
Genotoxic potential of a novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice (2020-01-01)
Morin-mediated regulation of apoptosis–autophagy crosstalk in Cancer: molecular mechanisms, preclinical evidence, and translational challenges (2026-01-01)
Transcriptomics-Guided Multi-Cohort Machine Learning for Alzheimer’s Disease Diagnosis (2026-01-01)
Blood-Based RNA Biomarkers and Machine Learning Approaches for Alzheimer’s Disease (2026-01-01)
Multi-omics biomarkers in cadmium-related lung toxicity and carcinogenesis (2026-01-01)
Neuroprotective effects of aegeline against LPS-induced memory dysfunction: involvement of hippocampal cholinergic/proinflammatory cytokines receptor modulation and insilico … (2026-01-01)
Marmelosin Protects Against Metabolic Disturbances in High-Fat Diet and Streptozotocin-Induced Diabetes (2025-01-01)
Therapeutic Potential of Lacidipine against 3-Nitropropionic Acid Induced Huntington's Disease: Based on Molecular Docking, Anti-Inflammatory and Neuroprotective Effects (2025-01-01)
Carbon tetrachloride and lung cancer (2025-01-01)
Environmental toxicants and lung cancer (2025-01-01)
Emergency Management and Surgical Repair of Abdominal Aortic Aneurysm: Comparing Open and Endovascular Approaches, Clinical Outcomes, and Survival Benefits (2024-01-01)
Efeitos anticonvulsivantes da desvenlafaxina na modulação da monoamina cerebral e do estresse oxidativo em camundongos (2023-01-01)
Thymoquinone-Loaded Nanomedicines for Triple-Negative Breast Cancer Treatment (2022-01-01)
The" Saudi guidelines for the prevention and management of obesity": awareness and adaptation in Al-Qassim province. (2022-01-01)
Protective Effect of Glucose-6-Phosphate Dehydrogenase and Dihydrofolate Reductase Against Diethylnitrosamine-Induced Hepatocellular Carcinoma in Rats (2022-01-01)
Nutraceuticals for Parkinson’s disease (2021-01-01)
Therapeutic Potential of Salvia Bucharica for Dyslipidemia and Vascular Dysfunction Induced through Two Different Pathways (2020-01-01)
An Overview of Hemophilia Diagnosis and Management in Children (2020-01-01)
Crystal structure of 5-(4-fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione, C9H8FN3S. (2019-01-01)
PRECLINICAL PHARMACOLOGICAL AND TOXICOLOGICAL STUDY OF NOVEL INHIBITORY KAPPA B KINASE ALPHA (IKKα) INHIBITOR COMPOUNDS IN PROSTATE CANCER (2016-01-01)
The Prediabetes Outcome at National Guard Primary Health Care Centers in Riyadh, Saudi Arabia: Retrospective Chart (2026-01-01)
Therapeutic potential of nanoemulsions as feasible wagons for targeting AlzheimerTs (2026-01-01)
Role of epithelial mesenchymal transitions marker in the different stage of endometriosis: expression of SNAIL, ZEB1, and TWIST gene (2026-01-01)
Dabigatran mitigates cisplatin-mediated nephrotoxicity through down regulation of thrombin pathway (2021-06-21)
Synergism of CD28 Immune Molecule in Late Immunosuppressive Phase of COVID-19: Effectiveness in Vaccinated Individuals (2023-04-01)
Aloesin mitigates cisplatin-induced nephrotoxicity by suppressing NF-κB-mediated oxidative stress and modulating Bax/Bcl-2/caspase pathways (2026-01-01)
Genotoxic potential of a novel PDE-4B inhibitor Apremilast by chromosomal aberration and micronucleus assay in mice (2020-05-01)
Aloesin mitigates cisplatin-induced nephrotoxicity by suppressing NF-κB-mediated oxidative stress and modulating Bax/Bcl-2/caspase pathways (2026-09-05)

المواد التدريسية