Khalid Saad Sharee Alharbi - Qassim...

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Faculty members

Khalid Saad Sharee Alharbi

Full Professor

College of Pharmacy,

section

Personal data

Scientific qualifications

Research interests

Published research

In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways (2025-01-24)
Effect of Sakuranetin Against Cyclophosphamide-Induced Immunodeficiency in Mice: Role of IFN-γ/TNF-α/IgG/IgM/Interleukins (2025-03-08)
Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling (2025-07-26)
p-Cymene inhibits pro-fibrotic and inflammatory mediators to prevent hepatic dysfunction (2025-04-15)
Effects of Rosiridin on a Rotenone-Induced Rat Model of Parkinson's Disease: An In Vivo Study and In Silico Molecular Modeling (2025-01-01)
Cubebin Attenuates Methamphetamine-Induced Neurotoxicity Through CREB/BDNF/Caspase-3 Signaling: An In Vivo and In Silico Study (2025-08-31)
Therapeutic Potential of Lacidipine Against 3-Nitropropionic Acid-Induced Huntington's Disease: Based on Molecular Docking, Anti-Inflammatory, and Neuroprotective Effects (2025-10-01)
EGF-functionalized lipid-polymer hybrid nanoparticles of 5-fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma (2021-11-25)
Biocompatible phospholipid-based nanovesicular drug delivery system of ketoprofen: Systematic development, optimization, and preclinical evaluation (2022-03-19)
Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3/NF-κB/Bcl-2 signaling pathways in rats and in silico study (2024-12-02)
Caffeic Acid Loaded Lipid-Polymer Hybrid Nanoparticles: Ex Vivo and Pre-clinical Evaluation Against Liver Cirrhosis (2022-09-01)
Implications of Solid Lipid Nanoparticles of Ganoderic Acid for the Treatment and Management of Hepatocellular Carcinoma (2020-05-30)
Promises of Phytochemical-Based Nano Drug Delivery Systems in Cancer Management (2021-11-16)
Development of Solid Lipid Nanoparticles as a Carrier for Pioglitazone to Enhance Oral Efficacy: Formulation Design Optimization, In Vitro Characterization, and In Vivo Biological Evaluation (2020-06-01)
Diosmin-loaded solid nanoparticles as a nano-antioxidant therapy for the management of hepatocellular carcinoma: QbD-based optimization, in vitro and in vivo evaluation (2021-02-10)
Implications of phospholipid-based nanomixed micelles of olmesartan medoxomil with enhanced lymphatic drug targeting and systemic bioavailability (2021-01-22)
Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma (2021-08-07)
Hibiscetin mitigates oxidative stress, nitrative stress, and neuroinflammation by suppressing TNF-α signaling in rotenone-induced parkinsonism in rats. (2022-12-21)
Oxyphenbutazone ameliorates carfilzomib-induced cardiotoxicity in rats via inhibition of oxidative free radical burst and the NF-κB/IκB-α pathway (2023-12-22)
Formulation and characterization of polymeric nanoparticle of Rivastigmine for effective management of Alzheimer's disease (2024-03-28)
Exploring GAS5's impact on prostate cancer: Recent discoveries and emerging paradigms (2023-10-12)
GAS5: A pivotal lncRNA in diabetes mellitus pathogenesis and management (2023-11-27)
Apoptosis-Driven Synergistic Anticancer Efficacy of the Ethyl Acetate Extract of Memecylon sisparense Gamble Leaves and Doxorubicin in In Vitro and In Vivo Models of Triple-Negative Breast Cancer (2024-01-03)
The ncRNA-TGF-β axis: Unveiling new frontiers in colorectal cancer research (2024-01-23)
Noncoding RNAs in hepatitis: Unraveling the apoptotic pathways (2024-02-06)
Non-coding RNAs as therapeutic targets in Parkinson's Disease: A focus on dopamine (2024-10-11)
Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma (2022-03-22)
Systematic Development of Solid Lipid Nanoparticles of Abiraterone Acetate with Improved Oral Bioavailability and Anticancer Activity for Prostate Carcinoma Treatment (2022-05-09)
Formulation of Amorphous Ternary Solid Dispersions of Dapagliflozin Using PEG 6000 and Poloxamer 188: Solid-State Characterization, Ex Vivo Study, and Molecular Simulation Assessment (2020-08-04)
Formulation of Chitosan Polymeric Vesicles Containing Ciprofloxacin for Ocular Delivery: Box-Behnken Optimization, In Vitro Characterization, HET-CAM Irritation, and Antimicrobial Assessment (2020-06-05)
Nanotherapeutic systems for delivering cancer vaccines: recent advances (2020-06-01)
Anti-Huntington's Effect of Rosiridin via Oxidative Stress, AchE Inhibition, and Modulation of Succinate Dehydrogenase, Nitrite, and BDNF Levels Compared to 3-Nitropropionic Acid in Rodents (2022-08-01)
Europinidin Mitigates 3-NPA-Induced Huntington's Disease Symptoms in Rats: A Comprehensive Analysis of Oxidative Stress, Mitochondrial Enzyme Complex Activity, Pro-Inflammatory Markers and Neurotransmitter Alterations (2024-03-01)
Rosiridin Protects Against Aluminum Chloride-Induced Memory Impairment Through Modulation of the BDNF/NFκB/PI3K/Akt Pathway in Rats (2024-11-01)
Barbaloin Protects Against Pentylenetetrazol-Induced Cognitive Deficits in Rodents by Modulating Neurotransmitters and Inhibiting Oxidative-Free-Radical-Induced Inflammation (2024-06-01)
Long-Acting Paliperidone Parenteral Formulations Based on Polycaprolactone Nanoparticles; the Influence of Stabilizer and Chitosan on In Vitro Release, Protein Adsorption, and Cytotoxicity (2020-02-01)
Europinidin Enhances Healing by Modulating Antioxidant Processes in Experimentally Induced Stomach Ulcer Conditions (2022-01-01)
Rosiridin Attenuates Scopolamine-Induced Cognitive Impairments in Rats via Inhibition of Oxidative and Nitrative Stress-Mediated Caspase-3/9 and TNF-α Signaling Pathways (2022-09-01)
Oxyphenbutazone Improves Memory and Learning Impairments in LPS-Induced Neurotoxicity by Modulating TGF-β/NF-κB/IκB-α Pathways: An In Silico and In Vivo Study (2026-01-20)
Neuroprotective Effects of Aegeline Against LPS-Induced Memory Dysfunction: Involvement of Modulation of Hippocampal Cholinergic and Proinflammatory Cytokine Receptors and In Silico Insights (2026-01-07)
Marmelosin Protects Against Metabolic Disorders in a High-Fat Diet and Streptozotocin-Induced Diabetes (2025-01-01)
Aloesin alleviates imiquimod-induced psoriasis in the dermal layers by inhibiting interleukins and NF-κB signaling pathways (2025-12-01)
Public Perception of Renewable Energy as a Fossil Fuel Alternative in Saudi Arabia: A Case Study from Riyadh (2026-04-12)
Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3/NF-κB/Bcl-2 signaling pathways in rats and in silico study (vol. 398, p. 5895, 2024) (2026-03-11)
A Hybrid Convolutional-Transformer Approach for Accurate Electroencephalography (EEG)-Based Parkinson's Disease Detection (2025-05-28)
Exploring the Effects of Renewable Energy, Energy Consumption, and Industrial Growth on Saudi Arabia's Environmental Footprint: An Autoregressive Distributed Lag Analysis (2024-12-01)
Conceptual Design for an Advanced High-Field 30 MeV Superconducting Cyclotron for the Production of Medical Isotopes (2024-01-01)
A Magnet Design for an Advanced High-Field Superconducting Cyclotron for Medical Isotope Production (2024-09-15)
Anesthesia-Induced Changes in Genomic Expression Leading to Neurodegeneration (2024-01-01)
Innovative Pilot Plant for Capacitive Deionization of Brackish Water for Desalination (2024-02-01)
Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation (2023-09-27)
The Potential of Molecular Pharmaceutics in the Development of Novel Drug Delivery Formulations (2023-01-01)
The Role of Flavonoids in Managing Various Biological Targets in Alzheimer's Disease: Evidence from Preclinical to Clinical Studies (2023-01-01)
Detection of Circulating Tumor Cells and Epithelial Progenitor Cells: A Comprehensive Study (2023-01-01)
Revealing the genetic links between Type 2 diabetes and the development of Alzheimer's disease (2023-01-21)
The Anticancer and EGFR-TK/CDK-9 Dual Inhibitory Potentials of New Synthetic Pyranopyrazole and Pyrazolone Derivatives: X-ray Crystallography, In Vitro, and In Silico Mechanistic Investigations (2023-01-10)
Polysaccharide-Based Nanomedicines Targeting Lung Cancer (2022-12-01)
PI3K/Akt/mTOR Pathway Inhibitors with Potential Prospects in Non-Small-Cell Lung Cancer (2022-01-01)
Gingerol, a Natural Antioxidant, Reduces Hyperglycemia and Related Complications (2022-12-01)
Barriers and facilitators of childhood COVID-19 vaccination among parents: A systematic review (2022-11-24)
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction (2022-08-25)
Formulation of intranasal surface-engineered nanostructured lipid carriers of rotigotine: full factorial design optimization, in vitro characterization, and pharmacokinetic evaluation (2022-10-01)
Oligonucleotides: A Novel Area of Interest for Drug Delivery in Neurodegenerative Diseases (2022-10-12)
Effects of the Anthocyanin Hirsutidin on Gastric Ulcers: Improved Healing through Antioxidant Mechanisms (2022-10-10)
A study of the molecular mechanism of quercetin and dasatinib combination as senolytics in alleviating age-related and kidney diseases (2022-10-21)
An Overview of Epidermal Growth Factor Receptor (EGFR) Inhibitors in Cancer Therapy (2022-08-27)
Therapeutic approaches of nutraceuticals in the prevention of Alzheimer's disease (2022-09-28)
Potential role of nutraceuticals by targeting the Wnt/β-catenin and NF-κB pathways in the treatment of osteoarthritis (2022-09-27)
Role of Nutraceuticals Derived from Medicinal Plants as Potential Targets for Breast Cancer Treatment (2022-09-19)
Molecular Explanation of Wnt/βcatenin Antagonist Pyrvinium Mediated Calcium Equilibrium Changes in Aging Cardiovascular Disorders (2022-09-15)
Rosinidin Protects Streptozotocin-Induced Memory Impairment-Activated Neurotoxicity by Suppressing Oxidative Stress and Inflammatory Mediators in Rats (2022-08-01)
The therapeutic role of nutraceuticals targeting the Nrf2/HO-1 signaling pathway in liver cancer (2022-08-09)
Molecular Investigation of the Hidden Pleiotropic Effects of Azoles on Dermatophytes in Human Tinea Corporis Infections (2022-07-28)
Formulation and Evaluation of Moxifloxacin Loaded Bilosomes In-Situ Gel: Optimization to Antibacterial Evaluation (2022-07-01)
A narrative review on the biology of Piezo1 with platelet-rich plasma in cardiac cell regeneration (2022-08-25)
Sodium alginate-based drug delivery in the management of breast cancer (2022-06-07)
Pharmacological Evaluation of the Cardioprotective Potential of Berberis orthobotrys Bien. ex Aitch. (2022-01-01)
Cardioprotective Potential of Thymus linearis Benth (2022-01-01)
Synthesis and Characterization of Antibiotic-Loaded Biodegradable Citrate-Functionalized Mesoporous Hydroxyapatite Nanocarriers as an Alternative Treatment for Bone Infections (2022-05-01)
Impact of Lipid Nanocarriers with High Phospholipid Content on the Oral Bioavailability and Pharmacodynamic Performance of Genistein (2022-05-20)
Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre/Pro-biotics in Manipulating Microflora (2022-03-28)
Formulation of Genistein-β-cyclodextrin Ternary Inclusion Complex: In Vitro Characterization and Cytotoxicity Assessment Using a Breast Cancer Cell Line (2022-01-11)
Nuclear factor-kappa B (NF-κB) inhibition as a therapeutic target for plant nutraceuticals in mitigating inflammatory lung diseases (2022-02-01)
The Potential Protective Effect of Polygonum hydropiper L. Against the Development of Fructose-Induced Oxidative Stress and Metabolic Disorders in Male Sprague-Dawley Rats (2021-06-22)
Bioactive Luteolin Entrapped Chitosan-PLGA Nanoparticles: Formulation Optimization to In-Vivo Preclinical Evaluation (2022-02-07)
Anti-Huntington's Effect of Butin in 3-Nitropropionic Acid-Treated Rats: Possible Mechanism of Action (2022-01-04)
6-Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α, IL-1β, and BDNF: Insight into the Mechanism (2021-12-28)
Therapeutic potential of nanoemulsions as feasible carriers for targeting Alzheimer's disease (2021-11-29)
Formulation of Genistein-HP β Cyclodextrin-Poloxamer 188 Ternary Inclusion Complex: Solubility to Cytotoxicity Assessment (2021-12-01)
Gene Therapy Approach with an Emphasis on Growth Factors: Theoretical and Clinical Outcomes in Neurodegenerative Diseases (2021-10-15)
A Review on Epidermal Growth Factor Receptor's Role in Breast and Non-Small Cell Lung Cancer (2021-11-06)
Development of a Piperine-Loaded Solid Self-Nanoemulsifying Drug Delivery System: Optimization and In Vitro, Ex Vivo, and In Vivo Evaluation (2021-11-01)
Ethyl acetate extract of tara mira (Eruca sativa) alleviates inflammation and rheumatoid arthritis in rats (2021-09-01)
Formulation of Chitosan-Coated Piperine NLCs: Optimization, In Vitro Characterization, and In Vivo Preclinical Assessment (2021-08-31)
Formulation of carteolol chitosomes for ocular delivery: formulation optimization, ex vivo permeation, and ocular toxicity testing (2021-08-02)
Nuclear factor-kappa B and its role in inflammatory lung disease (2021-06-30)
The Role of Epithelial-to-Mesenchymal Transition Markers in Different Stages of Endometriosis: Expression of the Snail, Slug, ZEB1, and Twist Genes (2021-01-01)
Chitosan-ethyl cellulose microspheres of domperidone for nasal delivery: Preparation, in-vitro characterization, in-vivo study for pharmacokinetic evaluation and bioavailability enhancement (2021-04-20)
Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity (2021-03-01)
Methanolic extract of Cucumis melo reduces ethylene glycol-induced nephrolithiasis in Wistar rats (2021-04-09)
Nanomedicine in the Treatment of Breast Cancer: A Challenge to Conventional Therapy (2021-03-02)
Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems (2021-03-02)
Functionalized Mesoporous Silica Nanoparticles in Anticancer Therapeutics (2021-03-02)
Simultaneous analysis of several antihypertensive drugs in different combinations: Application for determination of drug degradation products and process impurities (2021-04-02)
Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of their carbonic anhydrase inhibitory activities (2021-03-25)
Calcium sensing receptor hyperactivation through viral envelope protein E of SARS-CoV-2: a novel target for cardio-renal damage in COVID-19 infection (2021-03-09)
Novel Nanotechnology Approaches for Diagnosis and Therapy of Breast, Ovarian, and Cervical Cancer in Females: A Review (2021-02-10)
RETRACTED: Appraisal of the Antiarthritic Potential of Prazosin via Inhibition of Proinflammatory Cytokine TNF-α: A Key Player in Rheumatoid Arthritis (2021-01-26)
Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity (2020-12-01)
Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage (2020-11-01)
Effects of Berberine on Intestinal Flora of Non-Alcoholic Fatty Liver Induced by High-Fat Diet Through 16S rRNA Gene Sequencing (2020-07-01)
Phytochemical Analysis and Reappraisal of the Diuretic Activity of Delphinium brunonianum Royle and Its Mechanism of Action in Experimental Rats (2020-07-01)
Study on the Vascular Mechanisms Underlying the Hypotensive Effect of Sorghum halepense (L.) Pers. (2020-09-01)
Blood Pressure-Lowering Effects of Ranunculus scleratus Linn. in Normal and Fructose-Induced Hypertensive Rats and an Assessment of the Underlying Mechanisms (2020-09-01)
Beta-catenin non-canonical pathway: A potential target for inflammatory and hyperproliferative state via expression of transglutaminase 2 in psoriatic skin keratinocyte (2020-09-07)
MG132 inhibits the expression of PBX3 through miRNAs by targeting Argonaute2 in hepatoma cells (2020-08-01)
Original Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca 2+-channel (2020-06-01)
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation, and in silico insights (2020-07-01)
Nucleic acid-loaded lipid-polymer nanohybrids as novel nanotherapeutics in anticancer therapy (2020-05-07)
Pharmacological appraisal of ligustrazine based cyclohexanone analogs as inhibitors of inflammatory markers (2020-04-30)
Superbranched polyglycerol nanostructures as drug delivery and theranostics tools for cancer treatment (2020-04-01)
Nasal Mucoadhesive Microspheres of Lercanidipine with Improved Systemic Bioavailability and Antihypertensive Activity (2020-03-24)
BBD-Based Development of Itraconazole Loaded Nanostructured Lipid Carrier for Topical Delivery: In Vitro Evaluation and Antimicrobial Assessment (2020-01-06)
Development of a Novel Solid Self-Nanoemulsifying Oral Delivery System Loaded with Dapagliflozin: Physicochemical Characterization and In Vivo Antidiabetic Activity (2019-12-01)
Protective Effect of RIVA Against Sunitinib-Induced Cardiotoxicity by Inhibiting Oxidative Stress-Mediated Inflammation: Probable Role of TGF-β and Smad Signaling (2019-11-06)
Non-Overparametrized Adaptive Backstepping Control of PWM DC-DC Non-Inverting Buck-Boost Power Converter (2019-01-01)
Stabilization Of SPMS Wind Generator With Boost Converter Using Backstepping Approach (2018-01-01)
Adaptive Backstepping Control of PWM DC-DC Boost Power Converter Considering Parasitic Elements Effect (2018-01-01)
Nanocolloidal lipidic carriers of olmesartan medoxomil surface-tailored with Concavalin-A for lectin receptor targeting (2018-12-01)
Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma (2019-01-01)
Morin-mediated regulation of apoptosis-autophagy crosstalk in Cancer: molecular mechanisms, preclinical evidence, and translational challenges (2026-06-19)
Multi-omics biomarkers in cadmium-related lung toxicity and carcinogenesis (2026-04-15)
Electrochemical biosensors for MMP-9 in hepatitis B liver inflammation (2025-12-01)
Effect of Tirzepatide on Cisplatin and Doxorubicin-Induced Cardiotoxicity and Nephrotoxicity (2025-01-01)
Silencing of tissue factor by antisense deoxyoligonucleotide mitigates thioacetamide-induced liver injury (2020-05-20)
The use of sectional matrix in the direct restoration of a structurally compromised posterior tooth: a clinical technique (2019-10-01)
Nigella sativa oil alleviates doxorubicin-induced cardiomyopathy and neurobehavioral changes in mice: An in vivo and in silico study (2022-07-01)
An insight into the implications of estrogen deficiency and transforming growth factor β in antiepileptic drugs-induced bone loss (2021-07-08)
Three 'D's: Design approach, dimensional printing, and drug delivery systems as promising tools in healthcare applications (2021-11-19)
Lipid/polymer-based nanocomplexes for nucleic acid delivery in cancer vaccines (2021-08-27)
Biocompatible Polymeric Nanoparticles for Effective Codelivery of Tamoxifen with Ganoderic Acid A: A Systematic Approach for Improved Breast Cancer Therapeutics (2022-07-25)
Autologous Stem Cell Transplant in Hodgkin's and Non-Hodgkin's Lymphoma, Multiple Myeloma, and AL Amyloidosis (2023-12-01)
Nuclear factor-kappa B and its role in inflammatory lung disease (2021-01-01)
Nanomedicine in treatment of breast cancer–A challenge to conventional therapy (2021-01-01)
Functionalized Mesoporous Silica Nanoparticles in Anticancer Therapeutics (2021-01-01)
Sodium alginate-based drug delivery in the management of breast cancer (2022-01-01)
A Review on Epidermal Growth Factor Receptor's Role in Breast and Non-Small Cell Lung Cancer (2022-01-01)
Polysaccharide-based nanomedicines targeting lung cancer (2022-01-01)
Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma (2019-01-01)
Gene therapy approach with an emphasis on growth factors: theoretical and clinical outcomes in neurodegenerative diseases (2022-01-01)
Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment (2021-01-01)
Nuclear factor-kappa B (NF-κB) inhibition as a therapeutic target for plant nutraceuticals in mitigating inflammatory lung diseases (2022-01-01)
Gingerol, a natural antioxidant, attenuates hyperglycemia and downstream complications (2022-01-01)
Role of medicinal plant‐derived nutraceuticals as a potential target for the treatment of breast cancer (2022-01-01)
An Overview of Epidermal Growth Factor Receptor (EGFR) Inhibitors in Cancer Therapy (2022-01-01)
Formulation and evaluation of moxifloxacin loaded bilosomes in-situ gel: optimization to antibacterial evaluation (2022-01-01)
Comparative effectiveness of EDTA and citric acid assisted phytoremediation of Ni contaminated soil by using canola (Brassica napus) (2022-01-01)
Formulation of intranasal surface engineered nanostructured lipid carriers of rotigotine: Full factorial design optimization, in vitro characterization, and pharmacokinetic … (2022-01-01)
BBD-based development of itraconazole loaded nanostructured lipid carrier for topical delivery: in vitro evaluation and antimicrobial assessment (2021-01-01)
Formulation of Chitosan Polymeric Vesicles of Ciprofloxacin for Ocular Delivery: Box-Behnken Optimization, In Vitro Characterization, HET-CAM Irritation, and ... (2020-01-01)
Design, click conventional and microwave syntheses, DNA binding, docking and anticancer studies of benzotriazole-1, 2, 3-triazole molecular hybrids with different pharmacophores (2021-01-01)
Development of solid lipid nanoparticle as carrier of pioglitazone for amplification of oral efficacy: formulation design optimization, in-vitro characterization and in-vivo ... (2020-01-01)
Novel therapeutic interventions in cancer treatment using protein and peptide-based targeted smart systems (2021-01-01)
Novel 1, 2, 4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity (2020-01-01)
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights (2020-01-01)
Design, synthesis and biological evaluation of new HDAC1 and HDAC2 inhibitors endowed with ligustrazine as a novel cap moiety (2020-01-01)
Exploring satisfaction level among outpatients regarding pharmacy facilities and services in the Kingdom of Saudi Arabia; a large regional analysis (2021-01-01)
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico … (2023-01-01)
Therapeutic potential of nanoemulsions as feasible wagons for targeting Alzheimer’s disease (2021-01-01)
The therapeutic role of nutraceuticals targeting the Nrf2/HO‐1 signaling pathway in liver cancer (2022-01-01)
Gut Microbiota Disruption in COVID-19 or Post-COVID Illness Association with severity biomarkers: A Possible Role of Pre/Pro-biotics in manipulating microflora (2022-01-01)
Promises of Phytochemical-Based Nano Drug Delivery Systems in Cancer Management (2022-01-01)
Long-acting paliperidone parenteral formulations based on polycaprolactone nanoparticles; the influence of stabilizer and chitosan on in vitro release, protein adsorption, and … (2020-01-01)
Systematic development of solid lipid nanoparticles of abiraterone acetate with improved oral bioavailability and anticancer activity for prostate carcinoma treatment (2022-01-01)
PI3K/Akt/mTOR pathways inhibitors with potential prospects in non-small-cell lung cancer (2022-01-01)
Development of novel dapagliflozin loaded solid self-nanoemulsifying oral delivery system: Physiochemical characterization and in vivo antidiabetic activity (2019-01-01)
Rosiridin attenuates scopolamine-induced cognitive impairments in rats via inhibition of oxidative and nitrative stress leaded caspase-3/9 and TNF-α signaling pathways (2022-01-01)
Nucleic acid-loaded lipid-polymer nanohybrids as novel nanotherapeutics in anticancer therapy (2020-01-01)
Lipid/polymer-based nanocomplexes for nucleic acid delivery in cancer vaccines (2021-01-01)
Superbranched polyglycerol nanostructures as drug delivery and theranostics tools for cancer treatment (2021-01-01)
Nanotherapeutic systems for delivering cancer vaccines: Recent advances (2020-01-01)
A study of the molecular mechanism of quercetin and dasatinib combination as senolytic in alleviating age‐related and kidney diseases (2022-01-01)
6-Shogaol Attenuates Traumatic Brain Injury-Induced Anxiety/Depression-like Behavior via Inhibition of Oxidative Stress-Influenced Expressions of Inflammatory Mediators TNF-α … (2022-01-01)
Development of piperine-loaded solid self-nanoemulsifying drug delivery system: optimization, in-vitro, ex-vivo, and in-vivo evaluation (2021-01-01)
Therapeutic approaches of nutraceuticals in the prevention of Alzheimer's disease (2022-01-01)
Barriers and facilitators of childhood COVID-19 vaccination among parents: A systematic review (2022-01-01)
Formulation of genistein-hp β cyclodextrin-poloxamer 188 ternary inclusion complex: Solubility to cytotoxicity assessment (2021-01-01)
Role of Epithelial-to-Mesenchymal Transition Markers in Different Stages of Endometriosis: Expression of the Snail, Slug, ZEB1, and Twist Genes (2021-01-01)
Identification of N-phenyl-2-(phenylsulfonyl) acetamides/propanamides as new SLC-0111 analogues: synthesis and evaluation of the carbonic anhydrase inhibitory activities (2021-01-01)
Chitosan-ethyl cellulose microspheres of domperidone for nasal delivery: Preparation, in-vitro characterization, in-vivo study for pharmacokinetic evaluation and … (2021-01-01)
Nanocarriers-loaded with natural actives as newer therapeutic interventions for treatment of hepatocellular carcinoma (2021-01-01)
Novel Nanotechnology Approaches for Diagnosis and Therapy of Breast, Ovarian, and Cervical Cancer in Females: A Review (2021-01-01)
Formulation of Chitosan-Coated Piperine NLCs: Optimization, In Vitro Characterization, and In Vivo Preclinical Assessment: Formulation of Chitosan-Coated … (2021-01-01)
Formulation and characterization of polymeric nanoparticle of Rivastigmine for effective management of Alzheimer’s disease (2024-01-01)
Evaluation of anti-cancer effects of carnosine and melittin-loaded niosomes in MCF-7 and MDA-MB-231 breast cancer cells (2023-01-01)
Mucoadhesive in situ rectal gel loaded with rifampicin: Strategy to improve bioavailability and alleviate liver toxicity (2021-01-01)
Anaesthesia-induced changes in genomic expression leading to neurodegeneration (2024-01-01)
Beta-catenin non-canonical pathway: A potential target for inflammatory and hyperproliferative state via expression of transglutaminase 2 in psoriatic skin keratinocyte (2020-01-01)
Protective effect of RIVA against sunitinib-induced cardiotoxicity by inhibiting oxidative stress-mediated inflammation: probable role of TGF-β and Smad signaling (2020-01-01)
Potential role of nutraceuticals via targeting a Wnt/β‐catenin and NF‐κB pathway in treatment of osteoarthritis (2022-01-01)
Implications of solid lipid nanoparticles of ganoderic acid for the treatment and management of hepatocellular carcinoma (2021-01-01)
Role of rivaroxaban in sunitinib-induced renal injuries via inhibition of oxidative stress-induced apoptosis and inflammation through the tumor necrosis factor-α induced... (2020-01-01)
EGF‐functionalized lipid–polymer hybrid nanoparticles of 5‐fluorouracil and sulforaphane with enhanced bioavailability and anticancer activity against colon carcinoma (2022-01-01)
Hispolon-loaded liquid crystalline nanoparticles: Development, stability, in vitro delivery profile, and assessment of hepatoprotective activity in hepatocellular carcinoma (2022-01-01)
Nasal mucoadhesive microspheres of lercanidipine with improved systemic bioavailability and antihypertensive activity (2021-01-01)
Diosmin-loaded solid nanoparticles as nano-antioxidant therapy for management of hepatocellular carcinoma: QbD-based optimization, in vitro and in vivo evaluation (2021-01-01)
Detection of circulating tumor cells and epithelial progenitor cells: A comprehensive study (2023-01-01)
Anti-Huntington’s effect of butin in 3-nitropropionic acid-treated rats: possible mechanism of action (2022-01-01)
A narrative review on the biology of Piezo1 with platelet-rich plasma in cardiac cell regeneration (2022-01-01)
Formulation of Genistein-β-cyclodextrin Ternary Inclusion Complex: In Vitro Characterization and Cytotoxicity Assessment Using a Breast Cancer Cell Line (2022-01-01)
Complete Blood-count-based Inflammatory Score (CBCS) of COVID-19 Patients at Tertiary Care Center. (2021-01-01)
Nanocolloidal lipidic carriers of olmesartan medoxomil surface-tailored with Concavalin-A for lectin receptor targeting (2018-01-01)
Rosiridin protects against aluminum chloride-induced memory impairment via modulation of BDNF/NFκB/PI3K/Akt pathway in rats (2024-01-01)
Synthesis and characterization of antibiotic–loaded biodegradable citrate functionalized mesoporous hydroxyapatite nanocarriers as an alternative treatment for bone infections (2022-01-01)
Three ‘D’s: Design approach, dimensional printing, and drug delivery systems as promising tools in healthcare applications (2021-01-01)
Rosinidin protects streptozotocin-induced memory impairment-activated neurotoxicity by suppressing oxidative stress and inflammatory mediators in rats (2022-01-01)
6-Shogaol attenuated ethylene glycol and aluminium chloride induced urolithiasis and renal injuries in rodents (2021-01-01)
Effects of berberine on intestinal flora in high-fat diet-induced non-alcoholic fatty liver disease via 16S rRNA gene sequencing (2020-01-01)
Autologous stem cell transplant in hodgkin’s and non-hodgkin’s lymphoma, multiple myeloma, and al amyloidosis (2023-01-01)
Role of flavonoids in management of various biological targets in Alzheimer’s disease: evidence from preclinical to clinical studies (2023-01-01)
Dabigatran mitigates cisplatin-mediated nephrotoxicity through down regulation of thrombin pathway (2021-01-01)
Hibiscetin attenuates oxidative, nitrative stress and neuroinflammation via suppression of TNF-α signaling in rotenone induced parkinsonism in rats (2022-01-01)
Effects of the anthocyanin hirsutidin on gastric ulcers: improved healing through antioxidant mechanisms (2022-01-01)
Potential of natural bioactive compounds in management of diabetes: review of preclinical and clinical evidence (2021-01-01)
Inhibition of Bruton tyrosine kinase by acalabrutinib dampens lipopolysaccharide/galactosamine-induced hepatic damage (2020-01-01)
Pathophysiology and pathogenesis of inflammation (2023-01-01)
Bioactive luteolin entrapped chitosan-PLGA nanoparticles: formulation optimization to in-vivo preclinical evaluation (2023-01-01)
Formulation of carteolol chitosomes for ocular delivery: formulation optimization, ex-vivo permeation, and ocular toxicity examination (2021-01-01)
Formulation of amorphous ternary solid dispersions of dapagliflozin using PEG 6000 and Poloxamer 188: solid-state characterization, ex vivo study, and molecular… (2020-01-01)
GAS5: A pivotal lncRNA in diabetes mellitus pathogenesis and management (2024-01-01)
Anti-Huntington’s effect of Rosiridin via oxidative stress/ache Inhibition and modulation of succinate dehydrogenase, nitrite, and BDNF levels against 3-Nitropropionic acid in … (2022-01-01)
Nano lipidic carriers for codelivery of sorafenib and ganoderic acid for enhanced synergistic antitumor efficacy against hepatocellular carcinoma (2021-01-01)
Europinidin mitigates 3-NPA-induced Huntington’s disease symptoms in rats: a comprehensive analysis of oxidative stress, mitochondrial enzyme complex activity, pro-inflammatory […] (2024-01-01)
Revealing genetic links of type 2 diabetes that lead to the development of Alzheimer’s disease (2023-01-01)
Molecular Explanation of Wnt/βcatenin Antagonist Pyrvinium Mediated Calcium Equilibrium Changes in Aging Cardiovascular Disorders (2022-01-01)
Exploring GAS5's impact on prostate cancer: Recent discoveries and emerging paradigms (2023-01-01)
Impact of Lipid Nanocarriers with High Phospholipid Content on the Oral Bioavailability and Pharmacodynamic Performance of Genistein (2022-01-01)
Calcium sensing receptor hyperactivation through viral envelop protein E of SARS CoV2: A novel target for cardio‐renal damage in COVID‐19 infection (2021-01-01)
Anticonvulsant effects of desvenlafaxine on modulating brain monoamine and oxidative stress in mice (2021-01-01)
Protective effect of baicalein alone and losartan–baicalein combination therapy on doxorubicin-induced hepatotoxicity in rats (2020-01-01)
Oligonucleotides: A Novel Area of Interest for Drug Delivery in Neurodegenerative Diseases (2022-01-01)
Implications of phospholipid-based nanomixed micelles of olmesartan medoxomil with enhanced lymphatic drug targeting and systemic bioavailability (2021-01-01)
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction (2022-01-01)
Simultaneous analysis of several antihypertensive drugs in different combinations: Application for determination of drug degradation products and process impurities (2021-01-01)
Rosiridin prevents cisplatin-induced renal toxicity by inhibiting caspase-3/NF-κB/Bcl-2 signaling pathways in rats and in silico study (2025-01-01)
Formulation and optimization of Naringin polymeric nanoparticles: Optimization to in vivo evaluation (2023-01-01)
Biocompatible polymeric nanoparticles for effective codelivery of tamoxifen with ganoderic acid A: systematic approach for improved breast cancer therapeutics (2023-01-01)
Boswellic acid attenuates scopolamine-induced neurotoxicity and dementia in rats: possible mechanism of action (2021-01-01)
Silencing of tissue factor by antisense deoxyoligonucleotide mitigates thioacetamide-induced liver injury (2020-01-01)
Evaluation of ligustrazine-based synthetic compounds for their antiproliferative effects (2021-01-01)
Methanolic extract of Cucumis melo attenuates ethylene glycol-induced nephrolithiasis in Wistar rats (2021-01-01)
The Pre-diabetes Outcome at National Guard Primary Health Care Centers in Riyadh, Saudi Arabia: A Retrospective Chart Review (2020-01-01)
Effect of Sakuranetin Against Cyclophosphamide-Induced Immunodeficiency in Mice: Role of IFN-γ/TNF-α/IgG/IgM/Interleukins (2025-01-01)
Aegeline improves doxorubicin-induced liver toxicity by modulating oxidative stress and Bax/Bcl2/caspase/NF-κB signaling (2025-01-01)
Barbaloin protects pentylenetetrazol-induced cognitive deficits in rodents via modulation of neurotransmitters and inhibition of oxidative-free-radicals-led inflammation (2024-01-01)
The potential protective effect of Polygonum hydropiper L. against the development of fructose-induced oxidative stress and metabolic disorders in male... (2022-01-01)
An insight into the implications of estrogen deficiency and transforming growth factor β in antiepileptic drugs-induced bone loss (2021-01-01)
Dietary phytochemicals and their potential effects on type 2 diabetes mellitus (2019-01-01)
Apoptosis-driven synergistic anti-cancer efficacy of ethyl acetate extract of Memecylon sisparense Gamble leaves and doxorubicin in in-vitro and in-vivo models of triple ... (2024-01-01)
Molecular exploration of hidden pleiotropic activities of azoles on dermatophytes in human tinea corporis infection (2022-01-01)
Europinidin enhances healing through modulating antioxidant processes in Experimentally Induced-stomach Ulcer Condition (2022-01-01)
Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca2+-channel (2020-01-01)
Pharmacological appraisal of ligustrazine based cyclohexanone analogs as inhibitors of inflammatory markers (2020-01-01)
Effects of Rosiridin on a Rotenone-Induced Rat Model of Parkinson's Disease: An In Vivo Study and In Silico Molecular Modeling (2025-01-01)
In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways (2025-01-01)
Effect of tirzepatide on cisplatin- and doxorubicin-induced cardiotoxicity and nephrotoxicity (2025-01-01)
Anxiety, mindfulness and self-efficacy association among university healthcare specialties students in Al Qassim, Saudi Arabia: a cross-sectional study (2023-01-01)
Caffeic Acid Loaded Lipid Polymer Hybrid Nanoparticles: Ex Vivo and Pre-clinical Evaluation Against Liver Cirrhosis: Md. A. Barkat et al. (2023-01-01)
Synergism of CD28 Immune Molecule in Late Immunosuppressive Phase of COVID-19: Effectiveness in Vaccinated Individuals. (2023-01-01)
Fundamental aspects of targeted drug delivery (2021-01-01)
MG132 inhibits the expression of PBX3 through miRNAs by targeting Argonaute2 in hepatoma cells (2020-01-01)
Non-coding RNAs as therapeutic targets in Parkinson’s Disease: A focus on dopamine (2024-01-01)
Oxyphenbutazone ameliorates carfilzomib induced cardiotoxicity in rats via inhibition of oxidative free radical burst and NF-κB/IκB-α pathway (2024-01-01)
Biocompatible phospholipid‐based nanovesicular drug delivery system of ketoprofen: Systematic development, optimization, and preclinical evaluation (2023-01-01)
Hormone-related cancer mechanistic and nanomedicines: challenges and prospects (2022-01-01)
Cardioprotective potential of Thymus linearis Benth (2022-01-01)
Biomarkers as targeted herbal drug discovery: a pharmacological approach to nanomedicines (2021-01-01)
Phytochemical analysis and reappraisal of diuretic activity of Delphinium brunonianum Royle and its mode of action in experimental rats. (2020-01-01)
Impact of COVID-19 on nephrology patients: a mechanistic outlook for pathogenesis of acute kidney injury (2020-01-01)
p-Cymene inhibits pro-fibrotic and inflammatory mediators to prevent hepatic dysfunction (2025-01-01)
Promises of molecular pharmaceutics in the development of novel drug delivery formulations (2023-01-01)
Nigella sativa oil alleviates doxorubicin-induced cardiomyopathy and neurobehavioral changes in mice: In vivo: and: in-silico: study (2022-01-01)
Microbiome in asthma (2022-01-01)
Hormone Related Cancer Mechanistic and Nanomedicines (2022-01-01)
Ethyl-acetate extract of tara mira (Eruca sativa) alleviates the inflammation and rheumatoid arthritis in rats. (2021-01-01)
Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity. Pharmaceutics 2021, 13, 336 (2021-01-01)
Blood pressure lowering effects of Ranunculus scleratus Linn. in normal and fructose induced hypertensive rats and estimation of underlying mechanisms. (2020-01-01)
Aloesin alleviates imiquimod-induced psoriasis in the dermal layers by inhibiting interleukins and NF-κB signaling pathways (2025-01-01)
Electrochemical biosensors for MMP-9 in hepatitis B liver inflammation (2025-01-01)
Cubebin attenuates methamphetamine-induced neurotoxicity through CREB/BDNF/Caspase-3 signaling: in vivo and in silico study (2025-01-01)
Noncoding RNAs in hepatitis: Unraveling the apoptotic pathways (2024-01-01)
The ncRNA-TGF-β axis: unveiling new frontiers in colorectal cancer research (2024-01-01)
Phyto-actives and their targeted action in management of hepatocellular Carcinoma: scope of nanomedicine in its effective delivery (2022-01-01)
Bioactive-loaded Nanomedicine for the Management of Health and Disease (2022-01-01)
Pharmacological evaluation of cardioprotective potential of Berberis orthobotrys Bien. ex Aitch. (2022-01-01)
Oxyphenbutazone Improves Memory and Learning Impairments in LPS-Induced Neurotoxicity by Modulating TGF-β/NF-κB/IκB-α Pathways: An In Silico and In Vivo Study (2026-01-01)
Effect of mercury on gut microbiome (2025-01-01)
Epigenetic Optimization in Chronic Obstructive Pulmonary Disease (COPD) (2023-01-01)
A cross-sectional survey: The “Saudi guidelines for the prevention and management of obesity”: Awareness and adaptation in Al-Qassim province (2022-01-01)
Post-Traumatic Stress Disorder (PTSD) (2020-01-01)
Evaluation of effect of Acacia jacquemontii Benth. on blood pressure in normotensive and fructose induced hypertensive sprague dawley rats: An ethnopharmacological approach. (2020-01-01)
Study on vascular mechanisms underlying the hypotensive effect of Sorghum halepense (L.) Pers. (2020-01-01)
Genotoxic Potential of Apremilast, a Novel PDE-4B Inhibitor, as Assessed by Chromosomal Aberration and Micronucleus Assays in Mice (2020-01-01)
Morin-mediated regulation of apoptosis–autophagy crosstalk in Cancer: molecular mechanisms, preclinical evidence, and translational challenges (2026-01-01)
Transcriptomics-Guided Multi-Cohort Machine Learning for the Diagnosis of Alzheimer’s Disease (2026-01-01)
Blood-Based RNA Biomarkers and Machine Learning Approaches for Alzheimer’s Disease (2026-01-01)
Multi-omics biomarkers in cadmium-related lung toxicity and carcinogenesis (2026-01-01)
Neuroprotective effects of aegeline against LPS-induced memory dysfunction: involvement of hippocampal cholinergic/proinflammatory cytokine receptor modulation and in silico … (2026-01-01)
Marmelosin Protects Against Metabolic Disorders in a High-Fat Diet and Streptozotocin-Induced Diabetes (2025-01-01)
Therapeutic Potential of Lacidipine Against 3-Nitropropionic Acid-Induced Huntington's Disease: Based on Molecular Docking, Anti-Inflammatory, and Neuroprotective Effects (2025-01-01)
Carbon tetrachloride and lung cancer (2025-01-01)
Environmental toxicants and lung cancer (2025-01-01)
Emergency Management and Surgical Repair of Abdominal Aortic Aneurysms: A Comparison of Open and Endovascular Approaches, Clinical Outcomes, and Survival Benefits (2024-01-01)
Anticonvulsant Effects of Desvenlafaxine on the Modulation of Cerebral Monoamines and Oxidative Stress in Mice (2023-01-01)
Thymoquinone-Loaded Nanomedicines for Triple-Negative Breast Cancer Treatment (2022-01-01)
"The Saudi Guidelines for the Prevention and Management of Obesity": Awareness and Adoption in Al-Qassim Province. (2022-01-01)
Protective Effect of Glucose-6-Phosphate Dehydrogenase and Dihydrofolate Reductase Against Diethylnitrosamine-Induced Hepatocellular Carcinoma in Rats (2022-01-01)
Nutraceuticals for Parkinson’s disease (2021-01-01)
Therapeutic Potential of Salvia Bucharica for Dyslipidemia and Vascular Dysfunction Induced through Two Different Pathways (2020-01-01)
An Overview of Hemophilia Diagnosis and Management in Children (2020-01-01)
Crystal structure of 5-(4-fluorophenyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione, C9H8FN3S. (2019-01-01)
Preclinical Pharmacological and Toxicological Study of Novel Inhibitory Kappa B Kinase Alpha (IKKα) Inhibitor Compounds in Prostate Cancer (2016-01-01)
The Pre-diabetes Outcome at National Guard Primary Health Care Centers in Riyadh, Saudi Arabia: A Retrospective Chart Review (2026-01-01)
Therapeutic Potential of Nanoemulsions as Feasible Carriers for Targeting Alzheimer's (2026-01-01)
Role of epithelial mesenchymal transitions marker in the different stage of endometriosis: expression of SNAIL, ZEB1, and TWIST gene (2026-01-01)
Dabigatran mitigates cisplatin-mediated nephrotoxicity through down regulation of thrombin pathway (2021-06-21)
Synergism of CD28 Immune Molecule in Late Immunosuppressive Phase of COVID-19: Effectiveness in Vaccinated Individuals (2023-04-01)
Aloesin mitigates cisplatin-induced nephrotoxicity by suppressing NF-κB-mediated oxidative stress and modulating Bax/Bcl-2/caspase pathways (2026-01-01)
Genotoxic Potential of Apremilast, a Novel PDE-4B Inhibitor, as Assessed by Chromosomal Aberration and Micronucleus Assays in Mice (2020-05-01)
Aloesin mitigates cisplatin-induced nephrotoxicity by suppressing NF-κB-mediated oxidative stress and modulating Bax/Bcl-2/caspase pathways (2026-09-05)

Teaching materials