A simple icon, consisting of a series of links surrounded by a circle, is a common symbol for a connection or hyperlink. The lines of the icon are outlined in a dark black color on the background, with the addition of military elements of the Saudi national identity such as the Ghutra, Shamaa, and Saudi Bisht, to reflect the distinctive local character of Qassim University.
Links to official Saudi educational websites end with edu.sa
All links to official educational websites of government agencies in Saudi Arabia end with .edu.sa.
Black leather minimalist gesture tag, black circular grip, topped with a clear depiction of a Saudi tunic with a shamma and aqal, emphasizing the features of the Saudi bisht. This design symbolizes the concept of security and digital data privacy and reflects the identity of Qassim University.
protocol for encryption and security. HTTPS for encryption and security.
Secure websites in the Kingdom of Saudi Arabia use the HTTPS protocol for encryption.
Digital Government Authority

Registered with the Digital Government Authority with no: 20250413538

Qassim University logo
Open search engine
Search
MyQU Single Sign-On Portal
MyQU

Faculty members

Content

Inside a building, a man dressed in a traditional white uniform with a red and white Saudi shemagh wears a neutral expression as if he were taking a picture of a faculty file at Qassim University.
Photo of the faculty member

KAIS IBRAHIM MOHAMED AOUADI

College
section

Personal data

  • K.AOUADI@qu.edu.sa
  • Desktop watches
    Google Scholar
    OneDrive

    Scientific qualifications

    • University Qualification Certificate (UQC)
    • PhD specializing in organic chemistry
    • Master of Organic Chemistry
    • Professorship

    Research interests

    • Amino Acid Synthesis
    • 3,1-bipolar cyclic addition
    • Synthesis of chiral isoxazolidinediones
    • Heterogeneous ring manufacturing
    • https://scholar.google.com/citations?user=x9N7hO4AAAAJ&hl=fr

    Published research

    • Antimicrobial, Antioxidant, Anti-Acetylcholinesterase, Antidiabetic, and Pharmacokinetic Properties of Carum carvi L. and Coriandrum sativum L. Essential Oils … (2021-01-01)
    • Antioxidant Activities of a New Chemotype of *Piper cubeba* L. Fruit Essential Oil (Methyleugenol/Eugenol): In Silico Molecular Docking and ADMET Studies (2020-01-01)
    • Tomatidine and patchouli alcohol as inhibitors of SARS-CoV-2 enzymes (3CLpro, PLpro, and NSP15) by molecular docking and molecular dynamics simulations (2021-01-01)
    • Toward a treatment of antibacterial and antifungal infections: Design, synthesis, and in vitro activity of novel arylhydrazothiazolylsulfonamide analogues and their insight into… (2021-01-01)
    • Synthesis, in vitro antimicrobial assessment, and computational investigation of pharmacokinetic and bioactivity properties of novel trifluoromethylated compounds using in … (2020-01-01)
    • In vitro antimicrobial and α-glucosidase inhibitory potential of enantiopure cycloalkylglycine derivatives: Insights into their in silico pharmacokinetic, druglikeness, and … (2020-01-01)
    • HR-LCMS-Based Metabolite Profiling, Antioxidant, and Anticancer Properties of Teucrium polium L. Methanolic Extract: Computational and In Vitro Study (2020-01-01)
    • Divergent synthesis of a pochonin library targeting HSP90 and in vivo efficacy of identified inhibitor (2008-01-01)
    • Design, synthesis, in vitro anticancer and antimicrobial evaluation, SAR analysis, molecular docking and dynamic simulation of new pyrazoles, triazoles, and pyridazines based … (2022-01-01)
    • Allium subhirsutum L. as a Potential Source of Antioxidant and Anticancer Bioactive Molecules: HR-LCMS Phytochemical Profiling, In Vitro and In Vivo … (2020-01-01)
    • Design, synthesis, molecular properties, and in vitro antioxidant and antibacterial potential of novel enantiopure isoxazolidine derivatives (2020-01-01)
    • Novel fused pyridine derivatives containing a pyrimidine moiety as prospective tyrosyl-tRNA synthetase inhibitors: Design, synthesis, pharmacokinetics, and molecular docking studies (2020-01-01)
    • Synthesis, structure-activity relationship, and in silico studies of novel pyrazolothiazole and thiazolopyridine derivatives as prospective antimicrobial and anticancer agents (2021-01-01)
    • Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights (2009-01-01)
    • Design, synthesis, biological evaluation, and in silico studies of novel 1, 2, 3-triazole-linked benzoxazine-2,4-dione conjugates as potent antimicrobial, antioxidant, and anti… (2022-01-01)
    • Stereoselective synthesis of enantiopure N-substituted pyrrolidine-2,5-dione derivatives via 1,3-dipolar cycloaddition and assessment of their in vitro antioxidant and ... (2017-01-01)
    • Multifunctional isoxazolidine derivatives as α-amylase and α-glucosidase inhibitors (2020-01-01)
    • Design, synthesis, ADMET, and molecular docking of new imidazo[4,5-b]pyridine-5-thione derivatives as potential tyrosyl-tRNA synthetase inhibitors (2020-01-01)
    • Effect of the coordination of $\pi$-acceptor 4-cyanopyridine ligand on the structural and electronic properties of meso-tetra($p$-methoxyphenyl) and meso-tetra($p$-chlorophenyl porphyrins (2020-01-01)
    • GC/MS Profiling, Antibacterial, Anti-Quorum Sensing, and Antibiofilm Properties of Anethum graveolens L. Essential Oil: Molecular Docking Study and In-Silico ... (2023-01-01)
    • GC-MS Profiling, Vibriocidal, Antioxidant, Antibiofilm, and Anti-Quorum Sensing Properties of Carum carvi L. Essential Oil: In Vitro and In Silico Approaches (2022-01-01)
    • 1,3-Dipolar cycloaddition of a chiral nitrone to (E)-1,4-dichloro-2-butene: a new efficient synthesis of (2S,3S,4R)-4-hydroxyisoleucine (2012-01-01)
    • New substituted pyrazolones and dipyrazolotriazines as promising tyrosyl-tRNA synthetase and peroxiredoxin-5 inhibitors: Design, synthesis, molecular docking, and structure… (2021-01-01)
    • Novel enantiopure isoxazolidine and C-alkyl imine oxide derivatives as potential hypoglycemic agents: Design, synthesis, dual inhibitors of α-amylase and α-glucosidase, ADMET ... (2020-01-01)
    • Analogues of insulin secretagogue (2S, 3R, 4S)-4-hydroxyisoleucine: synthesis by 1,3-dipolar cycloaddition reactions of chiral nitrones to alkenes (2008-01-01)
    • HPLC/MS Phytochemical Profiling with Antioxidant Activities of Echium humile Desf. Extracts: ADMET Prediction and Computational Study Targeting Human … (2021-01-01)
    • Unprecedented stereoselective synthesis of 3-methylisoxazolidin-5-aryl-1,2,4-oxadiazoles via 1,3-dipolar cycloaddition and study of their in vitro antioxidant activity (2016-01-01)
    • Cycloadditions of chiral nitrones to racemic 3-substituted butenes: a direct access with kinetic resolution to enantiopure dihydroxylated amino acids (2006-01-01)
    • Multifunctional derivatives of spiropyrrolidine tethered indeno-quinoxaline heterocyclic hybrids as potent antimicrobial, antioxidant, and antidiabetic agents: design, synthesis… (2022-01-01)
    • In Vitro and In Silico Screening of Anti-Vibrio spp., Antibiofilm, Antioxidant and Anti-Quorum Sensing Activities of Cuminum cyminum L. Volatile Oil (2022-01-01)
    • LC-ESI/MS-Phytochemical Profiling with Antioxidant, Antibacterial, Antifungal, Antiviral, and In Silico Pharmacological Properties of Algerian Asphodelus Tenuifolius (Cav… (2021-01-01)
    • Cycloaddition of a chiral nitrone to allylic motifs: an access to enantiopure sugar-based amino acids displaying a stable glycosidic bond and to (4S)-4-hydroxy-L-ornithine (2012-01-01)
    • Phytochemical Profiling of *Allium subhirsutum* L. Aqueous Extract with Antioxidant, Antimicrobial, Antibiofilm, and Anti-Quorum Sensing Properties: In Vitro and In … (2022-01-01)
    • Bioactivities and in silico study of Pergularia tomentosa L. phytochemicals as potent antimicrobial agents targeting type IIA topoisomerase, TyrRS, and Sap1 … (2021-01-01)
    • Zinc(II) triazole meso-aryl-substituted porphyrins for UV-visible chloride and bromide detection. Adsorption and catalytic degradation of malachite green dye. (2020-01-01)
    • New synthetic routes toward enantiopure (2S, 3R, 4R)-4-hydroxyisoleucine by 1,3-dipolar cycloaddition of a chiral nitrone to C4 alkenes (2007-01-01)
    • In vitro and in silico evaluation of antiproliferative activity of new isoxazolidine derivatives targeting EGFR: design, synthesis, cell cycle analysis, and apoptotic inducers (2023-01-01)
    • In silico design, synthesis, and evaluation of novel enantiopure isoxazolidines as promising dual inhibitors of α-amylase and α-glucosidase (2024-01-01)
    • Emetine, a potent alkaloid for the treatment of SARS-CoV-2 targeting papain-like protease and non-structural proteins: pharmacokinetics, molecular docking and dynamic studies (2022-01-01)
    • Design, synthesis, and in vitro evaluation of isoxazolidine-isatin hybrids targeting two pathways for antidiabetic potential, along with multiscale molecular modeling approaches. (2024-01-01)
    • Phytochemical Profiling, Antimicrobial, Antibiofilm, Insecticidal, and Anti-Leishmanial Properties of Aqueous Extract from Juglans regia L. Root Bark: In Vitro and In Silico … (2023-01-01)
    • GC-MS/MS Analysis and Wound Repair Potential of Urtica dioica Essential Oil: In silico Modeling and In vivo Study in Rats (2025-01-01)
    • Synthesis, optical properties, DNA, β-cyclodextrin interaction, hydrogen isotope sensor, and computational study of a new enantiopure isoxazolidine derivative (ISoXD) (2024-01-01)
    • New Spiropyrrolothiazole Derivatives Bearing an Oxazolone Moiety as Potential Antidiabetic Agents: Design, Synthesis, Crystal Structure, Hirshfeld Surface Analysis, ADME, and… (2022-01-01)
    • HPLC-MS Profiling, Antioxidant, Antimicrobial, Antidiabetic, and Cytotoxicity Activities of Arthrocnemum indicum (Willd.) Moq. Extracts (2022-01-01)
    • Biological Activities Evaluation of Enantiopure Isoxazolidine Derivatives: In Vitro, In Vivo, and In Silico Studies (2019-01-01)
    • (2-Oxoindolin-3-ylidene)methyl)-1H-pyrazole and their fused derivatives: Design, synthesis, antimicrobial evaluation, DFT, chemical approach, in silico ADME and … (2022-01-01)
    • Synthesis of New Porphyrin Complexes: Evaluations on Optical, Electrochemical, and Electronic Properties, and Application as an Optical Sensor (2019-01-01)
    • Stereoselective synthesis of 1,2,3-triazolyl-functionalized isoxazolidines, via two consecutive 1,3-dipolar cycloadditions, as precursors of unnatural amino acids (2013-01-01)
    • A reversible optical sensor film for mercury ion discrimination based on an isoxazolidine derivative and exhibiting pH sensing (2022-01-01)
    • Phytochemical Profiling, Antimicrobial and α-Glucosidase Inhibitory Potential of Phenolic-Enriched Extracts of the Aerial Parts from Echium humile Desf.: In Vitro … (2022-01-01)
    • X-ray molecular structure characterization of a hexamethylenetetramine zinc(II) porphyrin complex: Catalytic degradation of toluidine blue dye, experimental and statistical... (2021-01-01)
    • Synthesis and SPAR exploration of new semicarbazone-triazole hybrids in search of potent antioxidant, antibacterial, and antifungal agents (2019-01-01)
    • Design, synthesis, biological evaluation, kinetic studies, and molecular modeling of imidazo-isoxazole derivatives targeting both α-amylase and α-glucosidase inhibitors (2024-01-01)
    • GC-MS profile, α-glucosidase inhibitory potential, antibacterial and antioxidant evaluation of Citrus aurantium (L.) peels essential oil (2021-01-01)
    • Novel routes to either racemic or enantiopure α-amino-(4-hydroxy-pyrrolidin-3-yl) acetic acid derivatives and biological evaluation of a new promising pharmacological scaffold (2015-01-01)
    • Synthesis, optical properties, DNA, β-cyclodextrin interactions, and antioxidant evaluation of a novel isoxazolidine derivative (ISoXD2): A multispectral and computational analysis (2024-01-01)
    • Multi-Step Synthesis and Biological Evaluation of Analogues of Insulin Secretagogue (2S,3R,4S)-4-Hydroxyisoleucine (2009-01-01)
    • Lapachol and (α/β)-lapachone as inhibitors of SARS-CoV-2 Main Protease (Mpro) and hACE-2: ADME properties, docking, and dynamic simulation approaches (2022-01-01)
    • Tripeptides from Allium subhirsutum L. extracts: Pharmacokinetic properties, toxicity prediction, and in silico study against SARS-CoV-2 enzymes and pro-inflammatory proteins (2021-01-01)
    • Unexpected synthesis of aziridines under Cu(I)-catalyzed Kinugasa conditions assisted by microwave irradiation (2016-01-01)
    • Stereoselective Synthesis of Enantiopure Cycloalkylglycines via 1,3-Dipolar Cycloaddition of a Chiral Nitrone to Cycloalkenes (2014-01-01)
    • A Cycloaddition–Cyclization Combined Approach to Enantiopure 3‐Glycinyl‐4‐hydroxypyrrolidines and 3‐Substituted 4‐Hydroxyprolines (2014-01-01)
    • Repurposing of anisomycin and oleandomycin as potential anti-SARS-CoV-2 virus agents targeting key enzymes using virtual computational approaches (2022-01-01)
    • Synthesis of some isoxazolidine and isoxazoline derivatives using nitrone-derived (-)-menthone via 1,3-dipolar cycloaddition with alkenes, alkynes, and cycloalkenes (2016-01-01)
    • Untargeted metabolomics approach based on UPLC-ESI-QTOF-MS/MS and evaluation of antioxidant and cytotoxic activities of Nepeta deflersiana Schweinf. ex Hedge supported by … (2025-01-01)
    • A stereoselective method for the synthesis of enantiopure 3-substituted 4-hydroxyproline derivatives via 1,3-dipolar cycloadditions (2016-01-01)
    • C-glycosyl amino-substituted hydro- and benzoquinones: Synthesis and preliminary biological evaluation (2007-01-01)
    • Synthesis of Semicyclic Dienes by Modified Julia Olefination of Vinyl Sulfones Derived from Carbohydrates (2007-01-01)
    • Fatty acid profiling and bioactive potential of date palm (Phoenix dactylifera) seed oil: antioxidant, antimicrobial, and α-glucosidase inhibitory activities (2025-01-01)
    • Synthesis, Molecular Docking and Anticancer Activity of New Substituted Pyridine-1,2,3-Triazole Hybrid N-Glycosides Via Click Chemistry (2024-01-01)
    • Optical and photoelectronic properties of a new material: Optoelectronic application (2020-01-01)
    • Unprecedented Synthesis of 4-Ylidene (3S)-3-hydroxy-1-aryl (alkyl)-pyrrolidine-2,5-diones Based on 1,3-Dipolar Cycloaddition of a Sugar-Derived Nitrone to N-Substituted ... (2019-01-01)
    • Evaluation of Antioxidant, Anti-inflammatory, Anti-hemolytic, and Enzyme Inhibitory Activities of Polysaccharide Derived from Opuntia stricta (Haw.) Haw. Pulp and … (2025-01-01)
    • Antioxidant and Antimicrobial Activities of Thyme (Thymus vulgaris L.) Essential Oil Growing Wild in Tunisia (2021-01-01)
    • Anti-ulcer activity of green synthesized selenium nanoparticles using Nigella sativa L. seed extract in rats (2025-01-01)
    • Comprehensive multispectral and computational study of isoxazolidine derivative ‘ISoXD3’: Synthesis, spectral characteristics, DNA binding, and comparative effects of allyl and… (2025-01-01)
    • Synthesis of a novel enantiopure imidazo-isoxazole derivatives and in silico prediction of ADME/pharmacokinetics properties (2023-01-01)
    • Mechanochemical Promoted Heterocycles: A Solvent-Free Route to Triazole Carbohydrates as Glycogen Phosphorylase Inhibitors (2022-01-01)
    • Unprecedented 3-O-methyl-3-C-trifluoromethyl-d-ribono-(and l-lyxono)-γ-lactones synthesized by nucleophilic trifluoromethylation of d-hexose-derived cyclic ketones (2016-01-01)
    • Study of the Regio- and Stereoselectivity of [3+2] Cycloaddition of Nitrile Oxides to Various Racemic 3-acyloxy and 3-hydroxybut-1-enes (2012-01-01)
    • Synthesis of Novel Thiosemicarbazones and Their Molecular Docking Simulations as Inhibitors of α-Amylase and α-Glycosidase Enzymes (2025-01-01)
    • Exploring the antioxidant potency of novel indolin-2-one-based imidazo-isoxazole hybrids: Design, synthesis, and computational studies (2025-01-01)
    • Exploring 1,3-dipolar cycloaddition reactions of nitrones with alkenes: Synthesis of isoxazolidine derivatives (2025-01-01)
    • Design, Characterization, and Molecular Docking Study of New Isoxazolidine-1,2,3-Triazole Hybrids (2024-01-01)
    • S. Ghannay Synthesis of (3S, 3aS, 6aS)-2-acetyl-N-methylhexahydrofuro [3, 4-d][1, 2] oxazole-3-carboxamide via an oxidative cleavage using m-CPBA. ADME approach: Ghannay et al (2022-01-01)
    • Synthesis and characterization of novel isoxazolidine-thiosemicarbazone hybrid derivatives as precursors of unnatural amino acids (2022-01-01)
    • Crystal structure of (1S, 2S, 2′R, 3a′S, 5R)-2′-[(5-bromo-1H-indol-3-yl)methyl]-2-isopropyl-5,5′-dimethyldihydro-2′H-spiro[cyclohexane-1,6′-imidazo[1,5-b… (2016-01-01)
    • Crystal structure of 5-chloromethyl-N-methyl-4-[(4-phenyl-1,2,3-triazol-1-yl)methyl]isoxazolidine-3-carboxamide (2016-01-01)
    • (1S, 2R, 2′ S, 3′a S, 5R)-2′-[(1S)-1-Hydroxyethyl]-2-isopropyl-5, 5′-dimethyl-3′, 3′a-dihydro-2′H-spiro[cyclohexane-1, 6′-imidazo[1, 5-b]isoxazol]-4′(5′H)-one (2007-01-01)
    • Interaction Studies of a Novel Enantiopure Isoxazolidine with DNA and β-Cyclodextrin: Binding and Antioxidant Properties (2026-01-01)
    • Neuroprotective effects of *Artemisia campestris* essential oil against chlorpyrifos-induced toxicity in rats supported by computational modelling (2025-01-01)
    • Protective effect of Arthrocnemum indicum ethanolic extract on hypercholesterolemic rats along with antioxidant and antimicrobial activities (2025-01-01)
    • . Click Chemistry: a promising approach for 1,2,3-triazole synthesis (2024-01-01)
    • Synthesis of New 1,2,3-Triazole Glycoside-Based Quinoline Systems via Click Cycloaddition (2023-01-01)
    • Preparation and characterization of ZnO nanoparticles incorporated by mechanical milling into cellulose for electrical insulator applications (2022-01-01)
    • Synthesis of (3S,3aS,6aS)-2-acetyl-N-methylhexahydrofuro[3,4- d][1,2]oxazole-3-carboxamide via oxidative cleavage using m-CPBA. ADME approach (2022-01-01)
    • Thymus vulgaris L. Essential Oil: Effect on Fatty Acid and Protein Oxidation in Little Tuna (Euthynnus alletteratus) Minced During Refrigerated Storage (2021-01-01)
    • Proceedings of the First Maghrebi Colloquium on Heterocyclic Chemistry: CMCH 1-2017 held on May 16 & 17, 2017 by the Tunisian Association of Heterocyclic Chemistry and its… (2020-01-01)
    • Additional Iconography for the Article: A Stereoselective Method for the Synthesis of Enantiopure 3-Substituted 4-Hydroxyproline Derivatives via 1,3-Dipolar Cycloadditions (2016-01-01)
    • Crystal structure of 2-isopropyl-5,7'-dimethyl-1',3',3a',6',8a',8b'-hexahydrospiro[cyclohexane-1,6'-furo[3,4-d]imidazo[1,5-b]isoxazol]-8'(7'H)-one (2016-01-01)
    • Pyrrolidine derivatives (2015-01-01)
    • Novel pyrrolidine derivatives (2015-01-01)
    • Synthesis of 4-hydroxyisoleucine analogs, a natural hypoglycemic agent (2006-01-01)
    • Synthesis of a novel enantiopure imidazo-isoxazole derivatives and in silico prediction of ADME/pharmacokinetics properties (2023-04-12)

    Teaching materials

    • General Chemistry Chem 202
    • Advanced Organic Chemistry Chem 640
    • Kim Spectra 442
    • Organic Chemistry Chem 249
    • Organic Chemistry 2. Chem340

    Suggestions

    Single Sign-On Portal
    Achievement
    E-learning
    Email
    Directory of services
    Query services

    Cookies

    This website uses special cookies to ensure ease of use, improve your browsing experience, and clarify the terms and policies related to About user privacy. By continuing to browse this website, you acknowledge that you accept the use of cookies and the terms of the Privacy Policy

    Accept