ELSAYED ABDELHADI HASSAN ELMORSY.

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Faculty members

ELSAYED ABDELHADI HASSAN ELMORSY

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Research interests

Published research

Localized Drug Delivery in Different Gastrointestinal Cancers: Navigating Challenges and Advancing Nanotechnological Solutions (2025-01-01)
E1231/NMN protects against experimental metabolic syndrome: the central role of SIRT1 in modulating AKT/Nrf2/NFκB signaling (2025-03-17)
Activation of SIRT1 by SRT1720 alleviates dyslipidemia, improves insulin sensitivity, and exhibits liver-protective effects in diabetic rats on a high-fat diet: New insights into the SIRT1/Nrf2/NFκB signaling pathway (2025-01-10)
Sirtuin 6-driven ASC deacetylation confers hepatoprotection: A promising approach to inflammasome inhibition in experimental NASH (2025-09-29)
E1231/SR647 protects against unilateral renal ischemia-reperfusion injury by modulating SIRT1/FOXO3 interactions with Nrf2 and NFκB pathways (2025-04-15)
Modulation of FOXO3a Nuclear Localization by Linagliptin (BI-1356) Reveals a New Therapeutic Target in Chronic Ulcerative Colitis (2025-04-15)
Diabetic retinopathy in focus: Update on treatment advances, pharmaceutical approaches, and new technologies (2025-10-05)
MDL-800 protects against inflammatory and metabolic dysfunction: role of SIRT6 in the cross-regulation of NFκB, AMPK, and PPAR signaling in rats (2025-09-01)
A Systems Biology Perspective on Childhood ADHD: Neurochemical Dysregulation, Brain-Behavior Interactions, and Emerging Therapeutics (2025-09-04)
High Serum Levels of Irisin, Visfatin, and Adiponectin as Potential Independent Risk Factors for Diabetic Nephropathy Progression in Patients With Type 2 Diabetes Mellitus (2025-05-01)
Potential Protective Effect of Curcumin Against Thioacetamide-Induced Testicular Injury in Male Rabbits (2025-11-27)
Innovative pH-responsive alginate-coated rosuvastatin-loaded chitosan nanoparticles: a targeted approach to inhibiting HMGB1-activated RAGE/TLR4-NFκB signaling in colonic inflammation in rats (2025-06-18)
Alvespimycin Exhibits Potential Anti-TGF-β Signaling in the Setting of a Proteasome Activator in Rats with Bleomycin-Induced Pulmonary Fibrosis: A Promising Novel Approach. (vol 16, 1123, 2023) (2025-07-07)
A novel combination therapy targets sonic hedgehog signaling by the dual inhibition of HMG-CoA reductase and HSP90 in rats with non-alcoholic steatohepatitis (2024-05-08)
Mechanistic insights into carvedilol's potential protection against doxorubicin-induced cardiotoxicity (2024-07-13)
Advances in understanding cisplatin-induced toxicity: Molecular mechanisms and protective strategies (2024-10-21)
The role of matrix metalloproteinase-2 and miR-196a2 in the pathogenesis and diagnosis of bronchial asthma (2024-03-13)
Nicardipine-chitosan nanoparticles alleviate thioacetamide-induced acute liver injury by targeting NFκB/NLRP3/IL-1β signaling in rats: Unraveling new roles beyond calcium channel blocking (2024-08-27)
Itraconazole halts hepatocellular carcinoma progression by modulating sonic hedgehog signaling in rats: A novel therapeutic approach (2024-01-04)
Linagliptin, a DPP-4 inhibitor, activates AMPK/FOXO3a and suppresses NFκB to mitigate the debilitating effects of diethylnitrosamine exposure in rat liver: Novel mechanistic insights (2024-02-29)
Nanoscale Systems for Local Activation of Hypoxia-Inducible Factor-1 Alpha: A New Approach in Diabetic Wound Management (2024-01-01)
Orexins in apoptosis: a dual regulatory role (2024-04-12)
Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis (2023-09-28)
Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis (2024-03-13)
PU-H71 (NSC 750424): A Molecular Masterpiece Targeting HSP90 in Cancer and Beyond (2024-11-05)
Alvespimycin Exhibits Potential Anti-TGF-β Signaling in the Setting of a Proteasome Activator in Rats with Bleomycin-Induced Pulmonary Fibrosis: A Promising Novel Approach (2023-08-01)
Breaking a mitochondrial danger-STING feed-forward amplifier preserves alveolar-capillary architecture and dampens interferon-chemokine signaling in acute lung injury (2026-04-18)
Lactose-decorated, alginate-coated chitosan nanoparticles loaded with Coomassie Brilliant Blue G-250 protect colonic barrier integrity in experimental colitis (2026-06-17)
VPS13C-mediated endoplasmic reticulum-lysosome tethering in neuronal stress responses (2026-06-26)
STING organelle stress sensing in the liver drives hepatocyte fate and remodeling (2026-06-17)
Structural Control of NLRP3 Inflammasome Assembly and the Emerging Microprotein Frontier (2026-06-09)
The nano-biointerface as a structural regulator of cell behavior: Interactions of extracellular vesicles, synthetic nanocarriers, and nanofibers with cells (vol 101, 103431, 2026) (2026-05-26)
NINJ1-Mediated Plasma Membrane Rupture in Lytic Cell Death: Mechanisms, Consequences, and Context (2026-05-21)
Ultrastructural organization of the neurovascular unit: Nano-scale perspectives on blood-brain barrier architecture (2026-05-02)
A Spatial-Mechanistic Design Map for Microenvironment-Responsive Nanomaterials in Solid Tumors (2026-04-04)
Enhanced antifungal and cytotoxic activity of essential oils encapsulated in polydopamine nanocapsules against Candida albicans and Pichia kudriavzevii (2026-03-19)
The nano-biointerface as a structural regulator of cell behavior: Interactions of extracellular vesicles, synthetic nanocarriers, and nanofibers with cells (2026-03-15)
Prognostic Impact of Preoperative Tumor Markers in Patients with Colorectal Carcinoma (2026-02-28)
Adenosine A2A Receptor as a Dual-Acting Molecular Switch: Glial Morphological Changes and Neurovascular Tissue Remodeling in Neuroinflammation and Neurodegeneration (2026-02-26)
FOXO3a-mediated structural and cellular remodeling in liver tissue: Implications for apoptosis and homeostasis (2026-02-21)
Green mycosynthesis of ZnO nanoparticles enhances antifungal defense against Fusarium equiseti through metabolic and gene expression modulation (2026-02-04)
AGK2 and nicotinamide riboside reveal SIRT2's protective role in a diabetic-dietary rat model of NASH via deacetylation of NLRP3, LKB1, and FOXO3a and restoration of AMPK-ACC/PGC-1α-Nrf2 signaling (2025-11-29)
The Effects of a Reproductive Health Voucher Program on Out-of-Pocket Family Planning and Safe Motherhood Service Expenses: A Yemeni Study (2025-07-17)
Completeness of Medical Records for Trauma Patients Admitted to the Emergency Department of a University Hospital in Upper Egypt (2021-01-25)
Synthesis, Spectral, Optical, and Anti-inflammatory Activity of Complexes Derived from 2-Aminobenzohydrazide with Some Rare Earths (2015-12-25)
Evaluation of the Anti-Inflammatory and Analgesic Effects of Cu(II) and Zn(II) Complexes Derived from 2-(naphthalen-1-yloxy)-N′-(1-(pyridin-2-1)ethylidene)acetohydrazide (2014-12-25)
POLYMER EFFECTS ON THE HYDRAULIC CONDUCTIVITY OF SALINE AND SODIC SOIL CONDITIONS (1991-12-25)
Activation of nicotinamide phosphoribosyltransferase protects against unilateral renal ischemia-reperfusion injury via the NAD+/SIRT1/PGC-1α signaling pathway and modulation of NFκB/TNF-α/IL-6 (2025-10-04)
Reprogramming the hepatic immune microenvironment with mirtazapine in early neoplastic transformation: Evidence from a diethylnitrosamine-induced rat model (2025-08-29)
Activation of AMPK/SIRT1/FOXO3a signaling by BMS-477118 (saxagliptin) mitigates chronic colitis in rats: uncovering new anti-inflammatory and antifibrotic roles (2024-09-18)
Engineered exosomal delivery of semaglutide activates SIRT1-FOXO3a-miR-124 signaling and protects against cortical neuroinflammation (2026-02-25)
Reprogramming lysosomal-purinergic crosstalk governs the synergistic attenuation of NLRP3 inflammasome activation by cyclodextrin-P2X7 blockade in diabetic rats (2026-02-13)
Engineering stem cell morphology and tissue architecture through nano-engineered materials (2026-06-14)
Targeted intranasal brain delivery of brilliant blue G via mucoadhesive spanlastic nanovesicles attenuates neuroinflammation by limiting cGAS-STING signaling (2026-01-16)
Dual-sensitive gelatin-coated chitosan microparticles for targeted pulmonary delivery of semaglutide: a novel approach to enhancing anti-inflammatory and anti-fibrotic effects (2025-09-06)
STA-9090 in combination with a statin exerts enhanced protective effects in rats fed a high-fat diet and exposed to diethylnitrosamine and thioacetamide (2024-09-04)
Modulating HSP90's control over the NFκB/NLRP3/Caspase-1 axis is a new therapeutic target in liver fibrosis management: Insights into the role of TAS-116 (Pimitespib) (2024-08-15)
Hedgehog signaling is a promising target for the treatment of hepatic fibrogenesis: A novel management strategy using itraconazole-loaded nanoparticles (2024-05-14)
CD38-driven NAD+ depletion governs crypt structure and barrier dysfunction in fluorouracil-induced colonic mucositis: From metabolic collapse to architectural remodeling (2026-07-18)

Teaching materials