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Faculty members

Content

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Photo of the faculty member

Faizul Azam

College
section

Personal data

    Scientific qualifications

    • PhD

    Research interests

    • DFT Calculations
    • Computational Chemistry
    • Medicinal Chemistry
    • Molecular Dynamics Simulation
    • Computer-Aided Drug Design (CADD)

    Published research

    • Targeting oxidative stress component in the therapeutics of epilepsy (2012-01-01)
    • Combating oxidative stress in epilepsy: design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl ... (2010-01-01)
    • Degree-based topological indices and polynomials of hyaluronic acid-curcumin conjugates (2020-01-01)
    • Breaking Down the Barriers to a Natural Antiviral Agent: Antiviral Activity and Molecular Docking of Erythrina speciosa Extract, Fractions, and the Major Compound (2020-01-01)
    • Anti-endotoxin effects of terpenoids fraction from Hygrophila auriculata in lipopolysaccharide-induced septic shock in rats (2015-01-01)
    • Design and synthesis of pyrazole-pyrazoline hybrids as cancer-associated selective COX-2 inhibitors (2020-01-01)
    • Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer's drugs: A computational investigation (2014-01-01)
    • Synthesis of some urea and thiourea derivatives of 3-phenyl/ethyl-2-thioxo-2, 3-dihydrothiazolo [4, 5-d] pyrimidine and their antagonistic effects on haloperidol-induced ... (2009-01-01)
    • Design, synthesis and anti-Parkinsonian evaluation of 3-alkyl/aryl-8-(furan-2-yl) thiazolo [5, 4-e][1, 2, 4] triazolo [1, 5-c] pyrimidine-2(3 H)-thiones against neuroleptic ... (2010-01-01)
    • Rutin as promising drug for the treatment of Parkinson's disease: an assessment of MAO-B inhibitory potential by docking, molecular dynamics and DFT studies (2019-01-01)
    • Chemotherapy-induced cardiotoxicity: a new perspective on the role of Digoxin, ATG7 activators, Resveratrol, and herbal drugs (2023-01-01)
    • Isolation, characterization, anti-MRSA evaluation, and in-silico multi-target anti-microbial validations of actinomycin X2 and actinomycin D produced by novel Streptomyces (2021-01-01)
    • NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer's disease: an investigation by docking, molecular dynamics, and DFT studies (2018-01-01)
    • Synthesis of some novel N 4-(naphtha [1, 2-d] thiazol-2-yl) semicarbazides as potential anticonvulsants (2009-01-01)
    • Synthesis of Schiff bases of naphtha[1,2-d]thiazol-2-amine and metal complexes of 2-(2′-hydroxy)benzylideneaminonaphthothiazole as potential antimicrobial ... (2007-01-01)
    • Topological indices and QSPR/QSAR analysis of some antiviral drugs being investigated for the treatment of COVID-19 patients (2020-01-01)
    • An in-silico analysis of ivermectin interaction with potential SARS-CoV-2 targets and host nuclear importin α (2022-01-01)
    • Molecular Docking and Prediction of Pharmacokinetic Properties of Dual Mechanism Drugs that Block MAO-B and Adenosine A2A Receptors for the Treatment of Parkinson's Disease (2012-01-01)
    • Adenosine A2A receptor antagonists as novel anti-Parkinsonian agents: a review of structure-activity relationships (2009-01-01)
    • Targeting SARS-CoV-2 main protease by teicoplanin: a mechanistic insight by docking, MM/GBSA and molecular dynamics simulation (2021-01-01)
    • The Dynamic Role of Curcumin in Mitigating Human Illnesses: Recent Advances in Therapeutic Applications (2024-01-01)
    • Non-alcoholic fatty liver disease: relation to juvenile obesity, lipid profile, and hepatic enzymes (2023-01-01)
    • Molecular Interaction Studies of Green Tea Catechins as Multitarget Drug Candidates for the Treatment of Parkinson's Disease: Computational and Structural Insights (2015-01-01)
    • Inclusion complex of clausenidin with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-colon cancer activity (2021-01-01)
    • Nano-engineered nerolidol-loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity: Probable role of NLRP3 inflammasome and caspase-1 (2020-01-01)
    • Molecular docking studies of 1-(substituted phenyl)-3-(naphtha[1,2-d]thiazol-2-yl) urea/thiourea derivatives with the human adenosine A2A receptor (2011-01-01)
    • Elucidation of Teicoplanin Interactions with Drug Targets Related to COVID-19 (2021-01-01)
    • Ester Prodrugs of Ketoprofen: Synthesis, in vitro Stability, in vivo Biological Evaluation, and in silico Comparative Docking Studies against COX-1 and COX-2. (2016-01-01)
    • Safety, Stability, and Therapeutic Efficacy of Long-Circulating TQ-Incorporated Liposomes: Implication in the Treatment of Lung Cancer (2022-01-01)
    • Oxasetin from Lophiostoma sp. of the Baltic Sea: identification, in silico binding mode prediction and antibacterial evaluation against fish pathogenic bacteria. (2013-01-01)
    • Structure-based design, synthesis, and molecular modeling studies of thiazolyl urea derivatives as novel anti-Parkinsonian agents (2012-01-01)
    • Synthesis of quinoline-attached furan-2(3H)-ones with anti-inflammatory and antibacterial properties, (2011-01-01)
    • Anti-inflammatory, analgesic and molecular docking studies of Lanostanoic acid 3-O-α-α-D-glycopyranoside isolated from Helichrysum stoechas (2020-01-01)
    • In Vitro and In Silico Approaches for the Antileishmanial Activity Evaluations of Actinomycins Isolated from Novel Streptomyces smyrnaeus Strain UKAQ_23 (2021-01-01)
    • Current Status of Novel Pyridine Fused Derivatives as Anticancer Agents: An Insight into Future Perspectives and Structure Activity Relationship (SAR) (2021-01-01)
    • Zerumbone binding to estrogen receptors: an in-silico investigation (2018-01-01)
    • Structure-based design, synthesis, molecular docking, and biological activities of 2-(3-benzoylphenyl) propanoic acid derivatives as dual mechanism drugs (2012-01-01)
    • On Ve-Degree and Ev-Degree Topological Properties of Hyaluronic Acid-Anticancer Drug Conjugates with QSPR (2021-01-01)
    • Zerumbone Induces Apoptosis in Breast Cancer Cells by Targeting αvβ3 Integrin Upon Co-Administration with TP5-iRGD Peptide (2019-01-01)
    • Structure-based design, synthesis, and molecular modeling studies of 1-(benzo[d]thiazol-2-yl)-3-(substituted aryl) urea derivatives as novel antiParkinsonian agents (2012-01-01)
    • Synthesis, DFT analyses, antiproliferative activity, and molecular docking studies of curcumin analogues (2022-01-01)
    • Experimental and Theoretical Insights on the Chemopreventive Effect of Liposomal Thymoquinone Against Benzo[a]pyrene-Induced Lung Cancer in Swiss Albino Mice (2022-01-01)
    • Synthesis, molecular docking, and in vivo antidiabetic evaluation of new benzylidene-2,4-thiazolidinediones as partial PPAR-γ agonists (2023-01-01)
    • Lipid-based nanoparticle formulation of diallyl trisulfide chemosensitizes the growth inhibitory activity of doxorubicin in a colorectal cancer model: A novel in vitro, in vivo ... (2022-01-01)
    • Effect of thymoquinone on high fat diet and STZ-induced experimental type 2 diabetes: A mechanistic insight by in vivo and in silico studies (2021-01-01)
    • Synthesis of some urea and thiourea derivatives of naphtha [1, 2-d] thiazol-2-amine as anti-Parkinsonian agents that cause neuroprotection against haloperidol-induced oxidative ... (2009-01-01)
    • New Paradigms of Old Psychedelics in Schizophrenia (2022-01-01)
    • Development and validation of a novel UPLC-MS/MS method for quantification of delafloxacin in plasma and aqueous humor for pharmacokinetic analyses (2020-01-01)
    • Effectiveness of estrogen and its derivatives over dexamethasone in the treatment of COVID-19 (2024-01-01)
    • The Enhanced Affinity of WRKY Strengthens Drought Tolerance in Tomato (Solanum lycopersicum L.): An Innovative Bioinformatics Study (2023-01-01)
    • Liposomal Ellagic Acid Alleviates Cyclophosphamide-Induced Toxicity and Eliminates Systemic Cryptococcus neoformans Infection in Leukopenic Mice (2021-01-01)
    • In silico and in vitro studies on the inhibition of laccase activity by Ellagic acid: Implications in drug designing for the treatment of Cryptococcal infections (2022-01-01)
    • The Effect of Liposomal Diallyl Disulfide and Oxaliplatin on Proliferation of Colorectal Cancer Cells: In Vitro and In Silico Analysis (2022-01-01)
    • Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release (2023-01-01)
    • Synthesis, characterization, and biological activity of polyketones (2013-01-01)
    • Neuroprotective effect of naphtha [1, 2-d] thiazol-2-amine in an animal model of Parkinson's disease (2009-01-01)
    • Structure-based drug design approach for identifying potential inhibitors of HER2-targeted breast cancer (2024-01-01)
    • Structural, functional, molecular, and biological evaluation of novel triterpenoids isolated from Helichrysum stoechas (L.) Moench. Collected from Mediterranean Sea bank (2022-01-01)
    • Synthesis and biological studies of oxoquinolines: Experimental and theoretical investigations (2022-01-01)
    • Synthesis and biological evaluation of some 4-thiazolidinones (2004-01-01)
    • Formulation, In Vitro and In Silico Evaluations of Anise (Pimpinella anisum L.) Essential Oil Emulgel with Improved Antimicrobial Effects (2023-01-01)
    • Therapeutic potential of free radical scavengers in neurological disorders (2010-01-01)
    • Toward the Discovery of a Novel Class of Leads for High Altitude Disorders by Virtual Screening and Molecular Dynamics Approaches Targeting Carbonic Anhydrase (2022-01-01)
    • An In-Silico Approach to Understanding the Structural Requirements and Pharmacophore Identification of Carbonic Anhydrase Inhibitors for Combating Oxidative Stress at High Altitudes (2022-01-01)
    • Ginger Components as Anti-Alzheimer Drugs: Focus on Drug Design (2017-01-01)
    • Synthesis and characterization of new unsaturated polyesters containing cyclopentapyrazoline moiety in the main chain (2010-01-01)
    • Synthesis and antimicrobial activities of some 5-(4'-pyridyl)-4-substituted benzylideneamino-3-mercapto (4H)-1,2,4-triazoles (2004-01-01)
    • In vitro and in silico evaluations of actinomycin X2 and actinomycin D as potent anti-tuberculosis agents (2023-01-01)
    • A Deep Dive into the Pharmacological and Clinical Aspects of Garlic (Allium sativum) (2022-01-01)
    • Host Cell and SARS-CoV-2-Associated Molecular Structures and Factors as Potential Therapeutic Targets (2021-01-01)
    • A simple validated HPTLC method for the analysis of flavonoids and molecular docking studies of a novel triterpenoid glycoside isolated from Carya illinoinensis bark with … (2022-01-01)
    • An in-silico approach to target multiple proteins involved in antimicrobial resistance using natural compounds produced by wild mushrooms (2024-01-01)
    • Exploring cyclopropylamine-containing cyanopyrimidines as LSD1 inhibitors: Design, synthesis, ADMET, MD analysis, and anticancer activity profiling (2024-01-01)
    • In Silico Investigation of Structural Requirements for AMPA Receptor Antagonism by Quinoxaline Derivatives (2013-01-01)
    • Adsorption of methotrexate on hyaluronic acid: A comparative DFT and molecular dynamics simulation insights (2024-01-01)
    • An insight into the implications of estrogen deficiency and transforming growth factor β in antiepileptic drugs-induced bone loss (2021-01-01)
    • Design, molecular docking, and MD simulation of novel estradiol-pyrimidine analogues as potential inhibitors of Mpro and ACE2 for COVID-19 (2024-01-01)
    • Development and Evaluation of Novel Encapsulated Isoeugenol-Liposomal Gel Carrier System for Methicillin-Resistant Staphylococcus aureus (2023-01-01)
    • Structure and electronic properties of the HA-CUR conjugate: An insight from the DFT perspective (2022-01-01)
    • Targeting tubulin protein by novel 3,5-disubstituted-1,2,4-triazole analogs as anticancer agents: Design, synthesis, in vitro, and in silico studies (2025-01-01)
    • Insights into the Therapeutic Targets and Molecular Mechanisms of Eruca sativa Against Colorectal Cancer: An Integrated Approach Combining Network … (2025-01-01)
    • A structure-based drug design approach for the identification of antiviral compounds targeting the chikungunya virus RdRp protein (2024-01-01)
    • Deciphering Campylobacter jejuni DsbA1 Protein Dynamics in the Presence of Anti-virulent Compounds: A Multi-Pronged Computer-Aided Approach (2025-01-01)
    • Solvent-free synthesis, anticancer activity, and in-silico studies of 7-hydroxy-4-methylquinolin-2(1H)-one analogues (2024-01-01)
    • The role of Aedes aegypti in inducing/aggravating IgE-mediated allergic airway disease: extensive computational studies for identification of allergenic proteins (2024-01-01)
    • Dynamic and thermodynamic impact of L94A, W100A, and W100L mutations on the D2 dopamine receptor bound to risperidone (2022-01-01)
    • Synthesis and characterization of polyesters based on a diethyl ketone moiety (2014-01-01)
    • Mechanistic insights into novel cyano-pyrimidine pendant chalcone derivatives as LSD1 inhibitors by docking, ADMET, MM/GBSA, and molecular dynamics simulation (2025-01-01)
    • Non-Beta-Blocker Medications with Beta-Blocker Like Properties: A Systematic Review of Side Effects (2025-01-01)
    • An immuno-informatics approach for annotating hypothetical proteins and designing a multi-epitope vaccine against the Mpox virus (2024-01-01)
    • Microsecond MD Simulations to Explore the Structural and Energetic Differences between Human RXRα-PPARγ vs. RXRα-PPARγ-DNA (2022-01-01)
    • Nigella sativa oil alleviates doxorubicin-induced cardiomyopathy and neurobehavioral changes in mice: In vivo: and: in-silico: study (2022-01-01)
    • Targeting the SARS-CoV-2 main protease with teicoplanin: a mechanistic insight from in silico studies (2020-01-01)
    • Targeting Mitochondrial Drp1 Dynamics in Neurodegenerative Diseases: A Comprehensive Drug Design Approach Using AutoDock Vina‐GPU, DFT, and Molecular Dynamics Simulations (2025-01-01)
    • Isolation, Characterization, and Anti-Inflammatory Effects of β-Sitosterol-β-D-Glucoside from Hygrophila auriculata: Experimental Validation, Molecular Docking, and Molecular ... (2024-01-01)
    • Green Synthesis of Oxoquinoline-1 (2H)-Carboxamide as Antiproliferative and Antioxidant Agents: An Experimental and In-Silico Approach to High Altitude Related Disorders (2022-01-01)
    • Advancements in chemistry and the recent medicinal importance of oxadiazole (2021-01-01)
    • Monotherapy versus combination therapy evaluation of FDA-approved TKIs targeting PDGFR for the treatment of thyroid cancer (2026-01-01)
    • Cracking the Sulfur Code: Garlic Bioactive Molecules as Multi-Target Blueprints for Drug Discovery (2025-01-01)
    • Thiazolidinedione-Pyrimidine Hybrid as Potential Antidiabetic Agents and Their Cardioprotective Effect (2025-01-01)
    • Preclinical and Molecular Docking Insights into the Chemopreventive Role of Fenugreek Seed Extract in a Murine Model of Colorectal Cancer (2025-01-01)
    • The Structural, Biological, and In-Silico Profiling of Novel Capryloyl Tetra-Glucoside and Aliphatic Ester Constituents from Abutilon indicum Offers New … (2022-01-01)
    • Synthesis and characterization of liquid crystalline poly(ether-ketone)s containing 1-benzyl-4-piperidone moiety as a pendant group (2022-01-01)
    • Pharmacological Recognition of Urea Derivatives in Brain Disorders (2012-01-01)
    • Modular Approach to In Silico Antiviral Multitarget Inhibitors: Molecular Docking, Dynamics, Principal Component Analysis, Clustering, and Energy Landscape (2026-01-01)
    • Arugula-derived isothiocyanates as novel agents for a potential regulator of AKR1B10 protein in breast cancer: an integrated transcriptomic and molecular docking approach (2025-01-01)
    • Computational Study of Chalcone-Cyanopyrimidine Hybrids as LSD1 Inhibitors: Assessing the Influence of FAD on Binding Affinity and Inhibition (2025-01-01)
    • Structural and Magneto-Optical Study on the Tetrahedrally Configured [CoCl2(1-allylimidazole)2] and Molecular Docking to Hypoxia-Inducible Factor-1α (2025-01-01)
    • In silico optimization of pyrimidine-thiazolidinedione hybrids targeting PPAR-γ: Design, docking, MM-GBSA, ADMET, and molecular dynamics simulation (2025-01-01)
    • Identifying a Novel Class of Lead Compounds for Monoacylglycerol Lipase Inhibition: An Integrated Computational Study (2025-01-01)
    • Isoniazid Derivatives as Potential Lipoxygenase-15 Inhibitors: In-vitro and In-silico Studies (2024-01-01)
    • Cytokines as Potential Therapeutic Targets (2006-01-01)

    Teaching materials

    • General Chemistry
    • Organic Chemistry
    • Medicinal Chemistry
    • Computer-Aided Drug Design and Discovery

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